Small D - Search Results

1

SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease.

Brown R, Dougan C, Ferris P, Delaney R, Houston CJ, Rodgers A, Downey DG, Mall MA, Connolly B, Small D, Weldon S, Taggart CC. Brown R, et al. Among authors: small d. Front Immunol. 2024 Sep 5;15:1433642. doi: 10.3389/fimmu.2024.1433642. eCollection 2024. Front Immunol. 2024. PMID: 39301022 Free PMC article.

2

A secretory leukocyte protease inhibitor variant with improved activity against lung infection.

Camper N, Glasgow AM, Osbourn M, Quinn DJ, Small DM, McLean DT, Lundy FT, Elborn JS, McNally P, Ingram RJ, Weldon S, Taggart CC. Camper N, et al. Among authors: small dm. Mucosal Immunol. 2016 May;9(3):669-76. doi: 10.1038/mi.2015.90. Epub 2015 Sep 16. Mucosal Immunol. 2016. PMID: 26376365 Free article.

3

Targeting of cathepsin S reduces cystic fibrosis-like lung disease.

Small DM, Brown RR, Doherty DF, Abladey A, Zhou-Suckow Z, Delaney RJ, Kerrigan L, Dougan CM, Borensztajn KS, Holsinger L, Booth R, Scott CJ, López-Campos G, Elborn JS, Mall MA, Weldon S, Taggart CC. Small DM, et al. Eur Respir J. 2019 Mar 28;53(3):1801523. doi: 10.1183/13993003.01523-2018. Print 2019 Mar. Eur Respir J. 2019. PMID: 30655278 Free article.

4

Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice.

Brown R, Small DM, Doherty DF, Holsinger L, Booth R, Williams R, Ingram RJ, Elborn JS, Mall MA, Taggart CC, Weldon S. Brown R, et al. Mediators Inflamm. 2021 Mar 19;2021:6682657. doi: 10.1155/2021/6682657. eCollection 2021. Mediators Inflamm. 2021. PMID: 33828414 Free PMC article.

5

Secretory Leucoprotease Inhibitor (SLPI) Promotes Survival during Acute Pseudomonas aeruginosa Infection by Suppression of Inflammation Rather Than Microbial Killing.

Osbourn M, Rodgers AM, Dubois AV, Small DM, Humphries F, Delagic N, Moynagh PN, Weldon S, Taggart CC, Ingram RJ. Osbourn M, et al. Biomolecules. 2022 Nov 22;12(12):1728. doi: 10.3390/biom12121728. Biomolecules. 2022. PMID: 36551159 Free PMC article.

6

Characterisation of eppin function: expression and activity in the lung.

Scott A, Glasgow A, Small D, Carlile S, McCrudden M, McLean D, Brown R, Doherty D, Lundy FT, Hamid UI, O'Kane CM, McAuley DF, Brodlie M, Tunney M, Elborn JS, Irwin CR, Timson DJ, Taggart CC, Weldon S. Scott A, et al. Among authors: small d. Eur Respir J. 2017 Jul 13;50(1):1601937. doi: 10.1183/13993003.01937-2016. Print 2017 Jul. Eur Respir J. 2017. PMID: 28705940 Free article.

7

Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome.

McKelvey MC, Abladey AA, Small DM, Doherty DF, Williams R, Scott A, Spek CA, Borensztajn KS, Holsinger L, Booth R, O'Kane CM, McAuley DF, Taggart CC, Weldon S. McKelvey MC, et al. Am J Respir Crit Care Med. 2022 Apr 1;205(7):769-782. doi: 10.1164/rccm.202107-1631OC. Am J Respir Crit Care Med. 2022. PMID: 35073247

8

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.

Small DM, Zani ML, Quinn DJ, Dallet-Choisy S, Glasgow AM, O'Kane C, McAuley DF, McNally P, Weldon S, Moreau T, Taggart CC. Small DM, et al. Mol Ther. 2015 Jan;23(1):24-31. doi: 10.1038/mt.2014.162. Epub 2014 Sep 5. Mol Ther. 2015. PMID: 25189740 Free PMC article.

9

PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC).

Dunne VL, Ghita-Pettigrew M, Redmond KM, Small DM, Weldon S, Taggart CC, Prise KM, Hanna GG, Butterworth KT. Dunne VL, et al. Among authors: small dm. Int J Mol Sci. 2024 Jul 17;25(14):7817. doi: 10.3390/ijms25147817. Int J Mol Sci. 2024. PMID: 39063060 Free PMC article.

10

Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field.

Ghita M, Dunne VL, McMahon SJ, Osman SO, Small DM, Weldon S, Taggart CC, McGarry CK, Hounsell AR, Graves EE, Prise KM, Hanna GG, Butterworth KT. Ghita M, et al. Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1231-1240. doi: 10.1016/j.ijrobp.2018.12.010. Epub 2018 Dec 12. Int J Radiat Oncol Biol Phys. 2019. PMID: 30552964

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