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Randomized, double-blind, phase 1a single-ascending dose and food effect studies assessing safety and pharmacokinetics of EC5026 in healthy volunteers.
Schmidt WK, Cortés-Puch I, McReynolds CB, Croston GE, Hwang SH, Yang J, Pedersen TL, Wagner KM, Pham TT, Hunt T, Hammock BD. Schmidt WK, et al. Among authors: mcreynolds cb. Clin Transl Sci. 2024 Sep;17(9):e70033. doi: 10.1111/cts.70033. Clin Transl Sci. 2024. PMID: 39300734 Free PMC article. Clinical Trial.
Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients.
Li D, Morisseau C, McReynolds CB, Duflot T, Bellien J, Nagra RM, Taha AY, Hammock BD. Li D, et al. Among authors: mcreynolds cb. Anal Chem. 2020 May 19;92(10):7334-7342. doi: 10.1021/acs.analchem.0c01115. Epub 2020 Apr 27. Anal Chem. 2020. PMID: 32253910 Free PMC article.
Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative.
Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. Hammock BD, et al. Among authors: mcreynolds cb. J Med Chem. 2021 Feb 25;64(4):1856-1872. doi: 10.1021/acs.jmedchem.0c01886. Epub 2021 Feb 7. J Med Chem. 2021. PMID: 33550801 Free PMC article.
21 results