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Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.
Oleksak P, Rysanek D, Vancurova M, Vasicova P, Urbancokova A, Novak J, Maurencova D, Kashmel P, Houserova J, Mikyskova R, Novotny O, Reinis M, Juda P, Hons M, Kroupova J, Sedlak D, Sulimenko T, Draber P, Chlubnova M, Nepovimova E, Kuca K, Lisa M, Andrys R, Kobrlova T, Soukup O, Janousek J, Prchal L, Bartek J, Musilek K, Hodny Z. Oleksak P, et al. Among authors: draber p. ACS Pharmacol Transl Sci. 2024 Aug 12;7(9):2755-2783. doi: 10.1021/acsptsci.4c00190. eCollection 2024 Sep 13. ACS Pharmacol Transl Sci. 2024. PMID: 39296273
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation.
Řehulka J, Jurášek M, Dráber P, Ivanová A, Gurská S, Ječmeňová K, Mokshyna O, Hajdúch M, Polishchuk P, Drašar PB, Džubák P. Řehulka J, et al. Among authors: draber p. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2367139. doi: 10.1080/14756366.2024.2367139. Epub 2024 Jun 21. J Enzyme Inhib Med Chem. 2024. PMID: 38904149 Free PMC article.
Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation.
Hsu AT, Bugajev V, Gottschalk TA, Demkova L, Potuckova L, Draberova L, Bambouskova M, Hagemann P, O'Brien CA, Riecan M, Kuda O, Tsantikos E, Draber P, Wright MD, van Spriel AB, Hibbs ML, Halova I. Hsu AT, et al. Among authors: draber p. Allergy. 2024 Dec 9. doi: 10.1111/all.16426. Online ahead of print. Allergy. 2024. PMID: 39651606 No abstract available.
TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.
Ujevic A, Knizkova D, Synackova A, Pribikova M, Trivic T, Dalinskaya A, Drobek A, Niederlova V, Paprckova D, De Guia R, Kasparek P, Prochazka J, Labaj J, Fedosieieva O, Roeck BF, Mihola O, Trachtulec Z, Sedlacek R, Stepanek O, Draber P. Ujevic A, et al. Among authors: draber p. Nat Commun. 2024 Nov 19;15(1):10013. doi: 10.1038/s41467-024-54399-4. Nat Commun. 2024. PMID: 39562788 Free PMC article.
ABIN1 is a negative regulator of effector functions in cytotoxic T cells.
Janusova S, Paprckova D, Michalik J, Uleri V, Drobek A, Salyova E, Chorfi L, Neuwirth A, Andreyeva A, Prochazka J, Sedlacek R, Draber P, Stepanek O. Janusova S, et al. Among authors: draber p. EMBO Rep. 2024 Aug;25(8):3456-3485. doi: 10.1038/s44319-024-00179-6. Epub 2024 Jun 14. EMBO Rep. 2024. PMID: 38877170 Free PMC article.
287 results