McCusker KP - Search Results

1

Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson's disease.

Minnella A, McCusker KP, Amagata A, Trias B, Weetall M, Latham JC, O'Neill S, Wyse RK, Klein MB, Trimmer JK. Minnella A, et al. Among authors: mccusker kp. PLoS One. 2024 Sep 18;19(9):e0309893. doi: 10.1371/journal.pone.0309893. eCollection 2024. PLoS One. 2024. PMID: 39292705 Free PMC article.

2

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase.

Hinman A, Holst CR, Latham JC, Bruegger JJ, Ulas G, McCusker KP, Amagata A, Davis D, Hoff KG, Kahn-Kirby AH, Kim V, Kosaka Y, Lee E, Malone SA, Mei JJ, Richards SJ, Rivera V, Miller G, Trimmer JK, Shrader WD. Hinman A, et al. Among authors: mccusker kp. PLoS One. 2018 Aug 15;13(8):e0201369. doi: 10.1371/journal.pone.0201369. eCollection 2018. PLoS One. 2018. PMID: 30110365 Free PMC article.

3

Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.

McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. McCusker KP, et al. J Am Chem Soc. 2012 Oct 31;134(43):18074-81. doi: 10.1021/ja307855d. Epub 2012 Oct 22. J Am Chem Soc. 2012. PMID: 23088750 Free PMC article.

4

The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.

McCusker KP, Fujimori DG. McCusker KP, et al. ACS Chem Biol. 2012 Jan 20;7(1):64-72. doi: 10.1021/cb200418f. Epub 2011 Dec 30. ACS Chem Biol. 2012. PMID: 22208312 Free PMC article. Review.

5

An active-site phenylalanine directs substrate binding and C-H cleavage in the alpha-ketoglutarate-dependent dioxygenase TauD.

McCusker KP, Klinman JP. McCusker KP, et al. J Am Chem Soc. 2010 Apr 14;132(14):5114-20. doi: 10.1021/ja909416z. J Am Chem Soc. 2010. PMID: 20302299

6

Modular behavior of tauD provides insight into the origin of specificity in alpha-ketoglutarate-dependent nonheme iron oxygenases.

McCusker KP, Klinman JP. McCusker KP, et al. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19791-5. doi: 10.1073/pnas.0910660106. Epub 2009 Nov 5. Proc Natl Acad Sci U S A. 2009. PMID: 19892731 Free PMC article.

7

18O kinetic isotope effects in non-heme iron enzymes: probing the nature of Fe/O2 intermediates.

Mirica LM, McCusker KP, Munos JW, Liu HW, Klinman JP. Mirica LM, et al. Among authors: mccusker kp. J Am Chem Soc. 2008 Jul 2;130(26):8122-3. doi: 10.1021/ja800265s. Epub 2008 Jun 7. J Am Chem Soc. 2008. PMID: 18540575 Free PMC article.

8

Mechanistic investigations of 1-aminocyclopropane 1-carboxylic acid oxidase with alternate cyclic and acyclic substrates.

Thrower J, Mirica LM, McCusker KP, Klinman JP. Thrower J, et al. Among authors: mccusker kp. Biochemistry. 2006 Oct 31;45(43):13108-17. doi: 10.1021/bi061097q. Biochemistry. 2006. PMID: 17059228

9

Use of a tyrosine hydroxylase mutant enzyme with reduced metal affinity allows detection of activity with cobalt in place of iron.

Ellis HR, McCusker KP, Fitzpatrick PF. Ellis HR, et al. Among authors: mccusker kp. Arch Biochem Biophys. 2002 Dec 15;408(2):305-7. doi: 10.1016/s0003-9861(02)00568-4. Arch Biochem Biophys. 2002. PMID: 12464285 No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

9 results

Search Page

Filters