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ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts.
Hoeft K, Koch L, Ziegler S, Zhang L, Luetke S, Tanzer MC, Mohanta D, Schumacher D, Schreibing F, Long Q, Kim H, Klinkhammer BM, Schikarski C, Maryam S, Baens M, Hermann J, Krieg S, Peisker F, De Laporte L, Schaefer GJ, Menzel S, Jankowski J, Humphreys BD, Wahida A, Schneider RK, Versele M, Boor P, Mann M, Sengle G, Hayat S, Kramann R. Hoeft K, et al. Among authors: sengle g. J Clin Invest. 2024 Sep 17;134(18):e170246. doi: 10.1172/JCI170246. J Clin Invest. 2024. PMID: 39286973 Free PMC article.
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding.
Troilo H, Zuk AV, Tunnicliffe RB, Wohl AP, Berry R, Collins RF, Jowitt TA, Sengle G, Baldock C. Troilo H, et al. Among authors: sengle g. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13063-8. doi: 10.1073/pnas.1404166111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157165 Free PMC article.
Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.
Sengle G, Carlberg V, Tufa SF, Charbonneau NL, Smaldone S, Carlson EJ, Ramirez F, Keene DR, Sakai LY. Sengle G, et al. PLoS Genet. 2015 Jun 26;11(6):e1005340. doi: 10.1371/journal.pgen.1005340. eCollection 2015 Jun. PLoS Genet. 2015. PMID: 26114882 Free PMC article.
Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.
Ono RN, Sengle G, Charbonneau NL, Carlberg V, Bächinger HP, Sasaki T, Lee-Arteaga S, Zilberberg L, Rifkin DB, Ramirez F, Chu ML, Sakai LY. Ono RN, et al. Among authors: sengle g. J Biol Chem. 2009 Jun 19;284(25):16872-16881. doi: 10.1074/jbc.M809348200. Epub 2009 Apr 6. J Biol Chem. 2009. PMID: 19349279 Free PMC article.
The matrilins--adaptor proteins in the extracellular matrix.
Wagener R, Ehlen HW, Ko YP, Kobbe B, Mann HH, Sengle G, Paulsson M. Wagener R, et al. Among authors: sengle g. FEBS Lett. 2005 Jun 13;579(15):3323-9. doi: 10.1016/j.febslet.2005.03.018. Epub 2005 Mar 22. FEBS Lett. 2005. PMID: 15943978 Free article. Review.
Molecular and cellular basis of scleroderma.
Eckes B, Moinzadeh P, Sengle G, Hunzelmann N, Krieg T. Eckes B, et al. Among authors: sengle g. J Mol Med (Berl). 2014 Sep;92(9):913-24. doi: 10.1007/s00109-014-1190-x. Epub 2014 Jul 18. J Mol Med (Berl). 2014. PMID: 25030650 Review.
75 results