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ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts.
Hoeft K, Koch L, Ziegler S, Zhang L, Luetke S, Tanzer MC, Mohanta D, Schumacher D, Schreibing F, Long Q, Kim H, Klinkhammer BM, Schikarski C, Maryam S, Baens M, Hermann J, Krieg S, Peisker F, De Laporte L, Schaefer GJ, Menzel S, Jankowski J, Humphreys BD, Wahida A, Schneider RK, Versele M, Boor P, Mann M, Sengle G, Hayat S, Kramann R. Hoeft K, et al. Among authors: long q. J Clin Invest. 2024 Sep 17;134(18):e170246. doi: 10.1172/JCI170246. J Clin Invest. 2024. PMID: 39286973 Free PMC article.
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner.
Hoeft K, Schaefer GJL, Kim H, Schumacher D, Bleckwehl T, Long Q, Klinkhammer BM, Peisker F, Koch L, Nagai J, Halder M, Ziegler S, Liehn E, Kuppe C, Kranz J, Menzel S, Costa I, Wahida A, Boor P, Schneider RK, Hayat S, Kramann R. Hoeft K, et al. Among authors: long q. Cell Rep. 2023 Feb 28;42(2):112131. doi: 10.1016/j.celrep.2023.112131. Epub 2023 Feb 18. Cell Rep. 2023. PMID: 36807143 Free PMC article.
Label-free single-cell RNA multiplexing leveraging genetic variability.
Hoeft K, Bleckwehl T, Schumacher D, Kim H, Meyer R, Long Q, Zhang L, Möller C, Clahsen-van Groningen MC, Babler A, Saritas T, Kurth I, Milting H, Hayat S, Kramann R. Hoeft K, et al. Among authors: long q. Nat Commun. 2024 Dec 5;15(1):10612. doi: 10.1038/s41467-024-54270-6. Nat Commun. 2024. PMID: 39638798 Free PMC article.
1,621 results