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Page 1
SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.
Rowntree LC, Audsley J, Allen LF, McQuilten HA, Hagen RR, Chaurasia P, Petersen J, Littler DR, Tan HX, Murdiyarso L, Habel JR, Foo IJH, Zhang W, Ten Berge ERV, Ganesh H, Kaewpreedee P, Lee KWK, Cheng SMS, Kwok JSY, Jayasinghe D, Gras S, Juno JA, Wheatley AK, Kent SJ, Rossjohn J, Cheng AC, Kotsimbos TC, Trubiano JA, Holmes NE, Pang Chan KK, Hui DSC, Peiris M, Poon LLM, Lewin SR, Doherty PC, Thevarajan I, Valkenburg SA, Kedzierska K, Nguyen THO. Rowntree LC, et al. Among authors: thevarajan i. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411428121. doi: 10.1073/pnas.2411428121. Epub 2024 Sep 16. Proc Natl Acad Sci U S A. 2024. PMID: 39284068 Free PMC article.
Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations.
Habel JR, Chua BY, Kedzierski L, Selva KJ, Damelang T, Haycroft ER, Nguyen TH, Koay HF, Nicholson S, McQuilten HA, Jia X, Allen LF, Hensen L, Zhang W, van de Sandt CE, Neil JA, Pragastis K, Lau JS, Jumarang J, Allen EK, Amanant F, Krammer F, Wragg KM, Juno JA, Wheatley AK, Tan HX, Pell G, Walker S, Audsley J, Reynaldi A, Thevarajan I, Denholm JT, Subbarao K, Davenport MP, Hogarth PM, Godfrey DI, Cheng AC, Tong SY, Bond K, Williamson DA, McMahon JH, Thomas PG, Pannaraj PS, James F, Holmes NE, Smibert OC, Trubiano JA, Gordon CL, Chung AW, Whitehead CL, Kent SJ, Lappas M, Rowntree LC, Kedzierska K. Habel JR, et al. Among authors: thevarajan i. JCI Insight. 2023 Apr 10;8(7):e167157. doi: 10.1172/jci.insight.167157. JCI Insight. 2023. PMID: 37036008 Free PMC article.
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.
Zhang W, Kedzierski L, Chua BY, Mayo M, Lonzi C, Rigas V, Middleton BF, McQuilten HA, Rowntree LC, Allen LF, Purcell RA, Tan HX, Petersen J, Chaurasia P, Mordant F, Pogorelyy MV, Minervina AA, Crawford JC, Perkins GB, Zhang E, Gras S, Clemens EB, Juno JA, Audsley J, Khoury DS, Holmes NE, Thevarajan I, Subbarao K, Krammer F, Cheng AC, Davenport MP, Grubor-Bauk B, Coates PT, Christensen B, Thomas PG, Wheatley AK, Kent SJ, Rossjohn J, Chung AW, Boffa J, Miller A, Lynar S, Nelson J, Nguyen THO, Davies J, Kedzierska K. Zhang W, et al. Among authors: thevarajan i. Nat Immunol. 2023 Jun;24(6):966-978. doi: 10.1038/s41590-023-01508-y. Epub 2023 May 29. Nat Immunol. 2023. PMID: 37248417 Free PMC article.
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses.
Koutsakos M, Rowntree LC, Hensen L, Chua BY, van de Sandt CE, Habel JR, Zhang W, Jia X, Kedzierski L, Ashhurst TM, Putri GH, Marsh-Wakefield F, Read MN, Edwards DN, Clemens EB, Wong CY, Mordant FL, Juno JA, Amanat F, Audsley J, Holmes NE, Gordon CL, Smibert OC, Trubiano JA, Hughes CM, Catton M, Denholm JT, Tong SYC, Doolan DL, Kotsimbos TC, Jackson DC, Krammer F, Godfrey DI, Chung AW, King NJC, Lewin SR, Wheatley AK, Kent SJ, Subbarao K, McMahon J, Thevarajan I, Nguyen THO, Cheng AC, Kedzierska K. Koutsakos M, et al. Among authors: thevarajan i. Cell Rep Med. 2021 Mar 16;2(3):100208. doi: 10.1016/j.xcrm.2021.100208. Epub 2021 Feb 5. Cell Rep Med. 2021. PMID: 33564749 Free PMC article.
Temporal differences in culturable severe acute respiratory coronavirus virus 2 (SARS-CoV-2) from the respiratory and gastrointestinal tracts in a patient with moderate coronavirus disease 2019 (COVID-19).
Audsley JM, Holmes NE, Mordant FL, Douros C, Zufan SE, Nguyen THO, Kedzierski L, Rowntree LC, Hensen L, Subbarao K, Kedzierska K, Nicholson S, Sherry N, Thevarajan I, Tran T, Druce J. Audsley JM, et al. Among authors: thevarajan i. Infect Control Hosp Epidemiol. 2022 Sep;43(9):1286-1288. doi: 10.1017/ice.2021.223. Epub 2021 May 10. Infect Control Hosp Epidemiol. 2022. PMID: 33966675 Free PMC article. No abstract available.
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity.
Zhang W, Chua BY, Selva KJ, Kedzierski L, Ashhurst TM, Haycroft ER, Shoffner-Beck SK, Hensen L, Boyd DF, James F, Mouhtouris E, Kwong JC, Chua KYL, Drewett G, Copaescu A, Dobson JE, Rowntree LC, Habel JR, Allen LF, Koay HF, Neil JA, Gartner MJ, Lee CY, Andersson P, Khan SF, Blakeway L, Wisniewski J, McMahon JH, Vine EE, Cunningham AL, Audsley J, Thevarajan I, Seemann T, Sherry NL, Amanat F, Krammer F, Londrigan SL, Wakim LM, King NJC, Godfrey DI, Mackay LK, Thomas PG, Nicholson S, Arnold KB, Chung AW, Holmes NE, Smibert OC, Trubiano JA, Gordon CL, Nguyen THO, Kedzierska K. Zhang W, et al. Among authors: thevarajan i. Nat Commun. 2022 May 19;13(1):2774. doi: 10.1038/s41467-022-30088-y. Nat Commun. 2022. PMID: 35589689 Free PMC article.
Blood transcriptome responses in patients correlate with severity of COVID-19 disease.
Wang Y, Schughart K, Pelaia TM, Chew T, Kim K, Karvunidis T, Knippenberg B, Teoh S, Phu AL, Short KR, Iredell J, Thevarajan I, Audsley J, Macdonald S, Burcham J, McLean A; PREDICT-19 consortium; Tang B, Shojaei M. Wang Y, et al. Among authors: thevarajan i. Front Immunol. 2023 Jan 20;13:1043219. doi: 10.3389/fimmu.2022.1043219. eCollection 2022. Front Immunol. 2023. PMID: 36741372 Free PMC article.
Clinical presentation and management of COVID-19.
Thevarajan I, Buising KL, Cowie BC. Thevarajan I, et al. Med J Aust. 2020 Aug;213(3):134-139. doi: 10.5694/mja2.50698. Epub 2020 Jul 17. Med J Aust. 2020. PMID: 32677734 Free PMC article. Review.
32 results