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SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.
Rowntree LC, Audsley J, Allen LF, McQuilten HA, Hagen RR, Chaurasia P, Petersen J, Littler DR, Tan HX, Murdiyarso L, Habel JR, Foo IJH, Zhang W, Ten Berge ERV, Ganesh H, Kaewpreedee P, Lee KWK, Cheng SMS, Kwok JSY, Jayasinghe D, Gras S, Juno JA, Wheatley AK, Kent SJ, Rossjohn J, Cheng AC, Kotsimbos TC, Trubiano JA, Holmes NE, Pang Chan KK, Hui DSC, Peiris M, Poon LLM, Lewin SR, Doherty PC, Thevarajan I, Valkenburg SA, Kedzierska K, Nguyen THO. Rowntree LC, et al. Among authors: lewin sr. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411428121. doi: 10.1073/pnas.2411428121. Epub 2024 Sep 16. Proc Natl Acad Sci U S A. 2024. PMID: 39284068 Free PMC article.
Bringing optimised COVID-19 vaccine schedules to immunocompromised populations (BOOST-IC): study protocol for an adaptive randomised controlled clinical trial.
Griffin DWJ, Dymock M, Wong G, Morrissey CO, Lewin SR, Cheng AC, Howard K, Marsh JA, Subbarao K, Hagenauer M, Roney J, Cunningham A, Snelling T, McMahon JH. Griffin DWJ, et al. Among authors: lewin sr. Trials. 2024 Jul 17;25(1):485. doi: 10.1186/s13063-024-08315-2. Trials. 2024. PMID: 39020446 Free PMC article.
Circulating capsid-antibody-complexes (CACs) drive intrahepatic complement deposition and inform subclinical liver inflammation in chronic hepatitis B.
Tang Y, Xu M, Wang C, Wu M, Hu L, Li J, Lu W, Zheng Y, Zhang M, Jiang X, Zhu C, Audsley J, Tangkijvanich P, Avihingsanon A, Song S, Liu S, Lewin SR, George J, Douglas MW, Ling Y, Yuan Z, Zhu L, Zhang Z, Zhang X. Tang Y, et al. Among authors: lewin sr. Antiviral Res. 2024 Nov;231:106017. doi: 10.1016/j.antiviral.2024.106017. Epub 2024 Oct 11. Antiviral Res. 2024. PMID: 39396554
Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence.
Varco-Merth B, Chaunzwa M, Duell DM, Marenco A, Goodwin W, Dannay R, Nekorchuk M, Shao D, Busman-Sahay K, Fennessey CM, Silipino L, Hull M, Bosche WJ, Fast R, Oswald K, Shoemaker R, Bochart R, MacAllister R, Labriola CS, Smedley JV, Axthelm MK, Davenport MP, Edlefsen PT, Estes JD, Keele BF, Lifson JD, Lewin SR, Picker LJ, Okoye AA. Varco-Merth B, et al. Among authors: lewin sr. PLoS Pathog. 2024 Aug 22;20(8):e1012496. doi: 10.1371/journal.ppat.1012496. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39173097 Free PMC article.
The roles of the kynurenine pathway in COVID-19 neuropathogenesis.
Dehhaghi M, Heydari M, Panahi HKS, Lewin SR, Heng B, Brew BJ, Guillemin GJ. Dehhaghi M, et al. Among authors: lewin sr. Infection. 2024 Oct;52(5):2043-2059. doi: 10.1007/s15010-024-02293-y. Epub 2024 May 27. Infection. 2024. PMID: 38802702 Free PMC article. Review.
HIV transcription persists in the brain of virally suppressed people with HIV.
Jamal Eddine J, Angelovich TA, Zhou J, Byrnes SJ, Tumpach C, Saraya N, Chalmers E, Shepherd RA, Tan A, Marinis S, Gorry PR, Estes JD, Brew BJ, Lewin SR, Telwatte S, Roche M, Churchill MJ. Jamal Eddine J, et al. Among authors: lewin sr. PLoS Pathog. 2024 Aug 8;20(8):e1012446. doi: 10.1371/journal.ppat.1012446. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39116185 Free PMC article.
Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?
Harper J, Betts MR, Lichterfeld M, Müller-Trutwin M, Margolis D, Bar KJ, Li JZ, McCune JM, Lewin SR, Kulpa D, Diallo DD, Lederman MM, Paiardini M. Harper J, et al. Among authors: lewin sr. Pathog Immun. 2024 Mar 1;8(2):115-157. doi: 10.20411/pai.v8i2.665. eCollection 2023. Pathog Immun. 2024. PMID: 38455668 Free PMC article.
378 results