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SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.
Rowntree LC, Audsley J, Allen LF, McQuilten HA, Hagen RR, Chaurasia P, Petersen J, Littler DR, Tan HX, Murdiyarso L, Habel JR, Foo IJH, Zhang W, Ten Berge ERV, Ganesh H, Kaewpreedee P, Lee KWK, Cheng SMS, Kwok JSY, Jayasinghe D, Gras S, Juno JA, Wheatley AK, Kent SJ, Rossjohn J, Cheng AC, Kotsimbos TC, Trubiano JA, Holmes NE, Pang Chan KK, Hui DSC, Peiris M, Poon LLM, Lewin SR, Doherty PC, Thevarajan I, Valkenburg SA, Kedzierska K, Nguyen THO. Rowntree LC, et al. Among authors: jayasinghe d. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411428121. doi: 10.1073/pnas.2411428121. Epub 2024 Sep 16. Proc Natl Acad Sci U S A. 2024. PMID: 39284068 Free PMC article.
CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers.
Galperin M, Farenc C, Mukhopadhyay M, Jayasinghe D, Decroos A, Benati D, Tan LL, Ciacchi L, Reid HH, Rossjohn J, Chakrabarti LA, Gras S. Galperin M, et al. Among authors: jayasinghe d. Sci Immunol. 2018 Jun 8;3(24):eaat0687. doi: 10.1126/sciimmunol.aat0687. Sci Immunol. 2018. PMID: 29884618
Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition.
Szeto C, Bloom JI, Sloane H, Lobos CA, Fodor J, Jayasinghe D, Chatzileontiadou DSM, Grant EJ, Buckle AM, Gras S. Szeto C, et al. Among authors: jayasinghe d. Int J Mol Sci. 2020 Sep 25;21(19):7081. doi: 10.3390/ijms21197081. Int J Mol Sci. 2020. PMID: 32992915 Free PMC article.
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Lineburg KE, Grant EJ, Swaminathan S, Chatzileontiadou DSM, Szeto C, Sloane H, Panikkar A, Raju J, Crooks P, Rehan S, Nguyen AT, Lekieffre L, Neller MA, Tong ZWM, Jayasinghe D, Chew KY, Lobos CA, Halim H, Burrows JM, Riboldi-Tunnicliffe A, Chen W, D'Orsogna L, Khanna R, Short KR, Smith C, Gras S. Lineburg KE, et al. Among authors: d orsogna l, jayasinghe d. Immunity. 2021 May 11;54(5):1055-1065.e5. doi: 10.1016/j.immuni.2021.04.006. Epub 2021 Apr 13. Immunity. 2021. PMID: 33945786 Free PMC article.
The presentation of SARS-CoV-2 peptides by the common HLA-A∗02:01 molecule.
Szeto C, Chatzileontiadou DSM, Nguyen AT, Sloane H, Lobos CA, Jayasinghe D, Halim H, Smith C, Riboldi-Tunnicliffe A, Grant EJ, Gras S. Szeto C, et al. Among authors: jayasinghe d. iScience. 2021 Feb 19;24(2):102096. doi: 10.1016/j.isci.2021.102096. Epub 2021 Jan 22. iScience. 2021. PMID: 33521593 Free PMC article.
Elevated BMI reduces the humoral response to SARS-CoV-2 infection.
Tong MZ, Sng JD, Carney M, Cooper L, Brown S, Lineburg KE, Chew KY, Collins N, Ignacio K, Airey M, Burr L, Joyce BA, Jayasinghe D, McMillan CL, Muller DA, Adhikari A, Gallo LA, Dorey ES, Barrett HL, Gras S, Smith C, Good-Jacobson K, Short KR. Tong MZ, et al. Among authors: jayasinghe d. Clin Transl Immunology. 2023 Dec 3;12(12):e1476. doi: 10.1002/cti2.1476. eCollection 2023. Clin Transl Immunology. 2023. PMID: 38050635 Free PMC article.
56 results