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21 results

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Page 1
Mechanistic pharmacokinetic-pharmacodynamic modeling and simulations of naloxone auto-injector 10 mg reversal of opioid-induced respiratory depression.
Yang TE, Del Bene F, Lavezzi SM, Iavarone L, Zhang J, Kim J, Gjurich B, Kessler C. Yang TE, et al. Among authors: iavarone l. CPT Pharmacometrics Syst Pharmacol. 2024 Oct;13(10):1722-1733. doi: 10.1002/psp4.13215. Epub 2024 Sep 16. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39283753 Free PMC article.
A Three-Part, Randomised Study to Investigate the Safety, Tolerability, Pharmacokinetics and Mode of Action of BC 007, Neutraliser of Pathogenic Autoantibodies Against G-Protein Coupled Receptors in Healthy, Young and Elderly Subjects.
Becker NP, Haberland A, Wenzel K, Göttel P, Wallukat G, Davideit H, Schulze-Rothe S, Hönicke AS, Schimke I, Bartel S, Grossmann M, Sinn A, Iavarone L, Boergermann JH, Prilliman K, Golor G, Müller J, Becker S. Becker NP, et al. Among authors: iavarone l. Clin Drug Investig. 2020 May;40(5):433-447. doi: 10.1007/s40261-020-00903-9. Clin Drug Investig. 2020. PMID: 32222912 Free PMC article. Clinical Trial.
Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.
Jones HM, Butt RP, Webster RW, Gurrell I, Dzygiel P, Flanagan N, Fraier D, Hay T, Iavarone LE, Luckwell J, Pearce H, Phipps A, Segelbacher J, Speed B, Beaumont K. Jones HM, et al. Among authors: iavarone le. Clin Pharmacokinet. 2016 Jul;55(7):875-887. doi: 10.1007/s40262-015-0365-0. Clin Pharmacokinet. 2016. PMID: 26895021 Clinical Trial.
Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.
Comley RA, Salinas CA, Slifstein M, Petrone M, Marzano C, Bennacef I, Shotbolt P, Van der Aart J, Neve M, Iavarone L, Gomeni R, Laruelle M, Gray FA, Gunn RN, Rabiner EA. Comley RA, et al. Among authors: iavarone l. J Pharmacol Exp Ther. 2013 Aug;346(2):311-7. doi: 10.1124/jpet.112.202895. Epub 2013 May 17. J Pharmacol Exp Ther. 2013. PMID: 23685546 Clinical Trial.
Occupancy of brain dopamine D3 receptors and drug craving: a translational approach.
Mugnaini M, Iavarone L, Cavallini P, Griffante C, Oliosi B, Savoia C, Beaver J, Rabiner EA, Micheli F, Heidbreder C, Andorn A, Merlo Pich E, Bani M. Mugnaini M, et al. Among authors: iavarone l. Neuropsychopharmacology. 2013 Jan;38(2):302-12. doi: 10.1038/npp.2012.171. Epub 2012 Sep 12. Neuropsychopharmacology. 2013. PMID: 22968817 Free PMC article.
Dose-related reduction in bupropion plasma concentrations by ritonavir.
Park J, Vousden M, Brittain C, McConn DJ, Iavarone L, Ascher J, Sutherland SM, Muir KT. Park J, et al. Among authors: iavarone l. J Clin Pharmacol. 2010 Oct;50(10):1180-7. doi: 10.1177/0091270009359524. Epub 2010 May 19. J Clin Pharmacol. 2010. PMID: 20484617
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