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Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Sandovici I, Fernandez-Twinn DS, Campbell N, Cooper WN, Sekita Y, Zvetkova I, Ferland-McCollough D, Prosser HM, Oyama LM, Pantaleão LC, Cimadomo D, Barbosa de Queiroz K, Cheuk CSK, Smith NM, Kay RG, Antrobus R, Hoelle K, Ma MKL, Smith NH, Geyer SH, Reissig LF, Weninger WJ, Siddle K, Willis AE, Lam BYH, Bushell M, Ozanne SE, Constância M. Sandovici I, et al. Among authors: smith nm. Cell Rep. 2024 Sep 24;43(9):114750. doi: 10.1016/j.celrep.2024.114750. Epub 2024 Sep 15. Cell Rep. 2024. PMID: 39283743 Free article.
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.
Hammerle CM, Sandovici I, Brierley GV, Smith NM, Zimmer WE, Zvetkova I, Prosser HM, Sekita Y, Lam BYH, Ma M, Cooper WN, Vidal-Puig A, Ozanne SE, Medina-Gómez G, Constância M. Hammerle CM, et al. Among authors: smith nm. PLoS Genet. 2020 Oct 15;16(10):e1009069. doi: 10.1371/journal.pgen.1009069. eCollection 2020 Oct. PLoS Genet. 2020. PMID: 33057429 Free PMC article.
Human genomic DNA is widely interspersed with i-motif structures.
Peña Martinez CD, Zeraati M, Rouet R, Mazigi O, Henry JY, Gloss B, Kretzmann JA, Evans CW, Ruggiero E, Zanin I, Marušič M, Plavec J, Richter SN, Bryan TM, Smith NM, Dinger ME, Kummerfeld S, Christ D. Peña Martinez CD, et al. Among authors: smith nm. EMBO J. 2024 Oct;43(20):4786-4804. doi: 10.1038/s44318-024-00210-5. Epub 2024 Aug 29. EMBO J. 2024. PMID: 39210146 Free PMC article.
Author Correction: Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
Louro H, Vettorazzi A, López de Cerain A, Spyropoulou A, Solhaug A, Straumfors A, Behr AC, Mertens B, Žegura B, Fæste CK, Ndiaye D, Spilioti E, Varga E, Dubreil E, Borsos E, Crudo F, Eriksen GS, Snapkow I, Henri J, Sanders J, Machera K, Gaté L, Le Hegarat L, Novak M, Smith NM, Krapf S, Hager S, Fessard V, Kohl Y, Silva MJ, Dirven H, Dietrich J, Marko D. Louro H, et al. Among authors: smith nm. Arch Toxicol. 2024 Oct;98(10):3513-3514. doi: 10.1007/s00204-024-03818-y. Arch Toxicol. 2024. PMID: 39080021 Free PMC article. No abstract available.
New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals - a PARC (Partnership for the Assessment of Risk from Chemicals) project.
Snapkow I, Smith NM, Arnesdotter E, Beekmann K, Blanc EB, Braeuning A, Corsini E, Sollner Dolenc M, Duivenvoorde LPM, Sundstøl Eriksen G, Franko N, Galbiati V, Gostner JM, Grova N, Gutleb AC, Hargitai R, Janssen AWF, Krapf SA, Lindeman B, Lumniczky K, Maddalon A, Mollerup S, Parráková L, Pierzchalski A, Pieters RHH, Silva MJ, Solhaug A, Staal YCM, Straumfors A, Szatmári T, Turner JD, Vandebriel RJ, Zenclussen AC, Barouki R. Snapkow I, et al. Among authors: smith nm. Front Toxicol. 2024 Apr 9;6:1339104. doi: 10.3389/ftox.2024.1339104. eCollection 2024. Front Toxicol. 2024. PMID: 38654939 Free PMC article. Review.
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps.
Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K. Jaylet T, et al. Among authors: smith nm. Front Toxicol. 2024 Mar 8;6:1285768. doi: 10.3389/ftox.2024.1285768. eCollection 2024. Front Toxicol. 2024. PMID: 38523647 Free PMC article.
213 results