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Page 1
Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes.
Shinde P, Willemsen L, Anderson M, Aoki M, Basu S, Burel JG, Cheng P, Dastidar SG, Dunleavy A, Einav T, Forschmiedt J, Fourati S, Garcia J, Gibson W, Greenbaum JA, Guan L, Guan W, Gygi JP, Ha B, Hou J, Hsiao J, Huang Y, Jansen R, Kakoty B, Kang Z, Kobie JJ, Kojima M, Konstorum A, Lee J, Lewis SA, Li A, Lock EF, Mahita J, Mendes M, Meng H, Neher A, Nili S, Olsen LR, Orfield S, Overton JA, Pai N, Parker C, Qian B, Rasmussen M, Reyna J, Richardson E, Safo S, Sorenson J, Srinivasan A, Thrupp N, Tippalagama R, Trevizani R, Ventz S, Wang J, Wu CC, Ay F, Grant B, Kleinstein SH, Peters B. Shinde P, et al. Among authors: thrupp n. bioRxiv [Preprint]. 2024 Sep 8:2024.09.04.611290. doi: 10.1101/2024.09.04.611290. bioRxiv. 2024. PMID: 39282381 Free PMC article. Preprint.
MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. Balusu S, et al. Among authors: thrupp n. Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14. Science. 2023. PMID: 37708272 Free PMC article.
microRNA-132 regulates gene expression programs involved in microglial homeostasis.
Walgrave H, Penning A, Tosoni G, Snoeck S, Davie K, Davis E, Wolfs L, Sierksma A, Mars M, Bu T, Thrupp N, Zhou L, Moechars D, Mancuso R, Fiers M, Howden AJM, De Strooper B, Salta E. Walgrave H, et al. Among authors: thrupp n. iScience. 2023 May 6;26(6):106829. doi: 10.1016/j.isci.2023.106829. eCollection 2023 Jun 16. iScience. 2023. PMID: 37250784 Free PMC article.
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.
Calafate S, Özturan G, Thrupp N, Vanderlinden J, Santa-Marinha L, Morais-Ribeiro R, Ruggiero A, Bozic I, Rusterholz T, Lorente-Echeverría B, Dias M, Chen WT, Fiers M, Lu A, Vlaeminck I, Creemers E, Craessaerts K, Vandenbempt J, van Boekholdt L, Poovathingal S, Davie K, Thal DR, Wierda K, Oliveira TG, Slutsky I, Adamantidis A, De Strooper B, de Wit J. Calafate S, et al. Among authors: thrupp n. Nat Neurosci. 2023 Jun;26(6):1021-1031. doi: 10.1038/s41593-023-01325-4. Epub 2023 May 15. Nat Neurosci. 2023. PMID: 37188873 Free PMC article.
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horré K, Fourne Y, Ronisz A, Silajdžić E, Penning A, Tosoni G, Callaerts-Vegh Z, D'Hooge R, Thal DR, Zetterberg H, Thuret S, Fiers M, Frigerio CS, De Strooper B, Salta E. Walgrave H, et al. Among authors: thrupp n. Cell Stem Cell. 2021 Oct 7;28(10):1805-1821.e8. doi: 10.1016/j.stem.2021.05.001. Epub 2021 May 24. Cell Stem Cell. 2021. PMID: 34033742 Free article.
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B. Sala Frigerio C, et al. Among authors: thrupp n. Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099. Cell Rep. 2019. PMID: 31018141 Free PMC article.