Willemse M - Search Results

1

Ameliorated cellular hallmarks of myotonic dystrophy in hybrid myotubes from patient and unaffected donor cells.

Raaijmakers RHL, Ausems CRM, Willemse M, Cumming SA, van Engelen BGM, Monckton DG, van Bokhoven H, Wansink DG. Raaijmakers RHL, et al. Among authors: willemse m. Stem Cell Res Ther. 2024 Sep 15;15(1):302. doi: 10.1186/s13287-024-03913-y. Stem Cell Res Ther. 2024. PMID: 39278936 Free PMC article.

2

CRISPR/Cas9-Induced (CTG⋅CAG)_n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.

van Agtmaal EL, André LM, Willemse M, Cumming SA, van Kessel IDG, van den Broek WJAA, Gourdon G, Furling D, Mouly V, Monckton DG, Wansink DG, Wieringa B. van Agtmaal EL, et al. Among authors: willemse m. Mol Ther. 2017 Jan 4;25(1):24-43. doi: 10.1016/j.ymthe.2016.10.014. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129118 Free PMC article.

3

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat.

André LM, van Cruchten RTP, Willemse M, Bezstarosti K, Demmers JAA, van Agtmaal EL, Wansink DG, Wieringa B. André LM, et al. Among authors: willemse m. Int J Mol Sci. 2019 Nov 13;20(22):5685. doi: 10.3390/ijms20225685. Int J Mol Sci. 2019. PMID: 31766224 Free PMC article.

4

(CTG)n repeat-mediated dysregulation of MBNL1 and MBNL2 expression during myogenesis in DM1 occurs already at the myoblast stage.

André LM, van Cruchten RTP, Willemse M, Wansink DG. André LM, et al. Among authors: willemse m. PLoS One. 2019 May 22;14(5):e0217317. doi: 10.1371/journal.pone.0217317. eCollection 2019. PLoS One. 2019. PMID: 31116797 Free PMC article.

5

The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells.

van der Bent ML, Paulino da Silva Filho O, Willemse M, Hällbrink M, Wansink DG, Brock R. van der Bent ML, et al. Among authors: willemse m. FASEB J. 2019 Oct;33(10):11314-11325. doi: 10.1096/fj.201900263R. Epub 2019 Jul 16. FASEB J. 2019. PMID: 31311315

Our findings have important implications for the clinical use of ASOs in DM1 and provide a basis for further research on other types of ASOs.-Van der Bent, M. L., Paulino da Silva Filho, O., Willemse, M., Hallbrink, M., Wansink, D. G., Brock, R. ...

Our findings have important implications for the clinical use of ASOs in DM1 and provide a basis for further research on other types of ASOs …

6

Intrinsic Myogenic Potential of Skeletal Muscle-Derived Pericytes from Patients with Myotonic Dystrophy Type 1.

Ausems CRM, Raaijmakers RHL, van den Broek WJAA, Willemse M, van Engelen BGM, Wansink DG, van Bokhoven H. Ausems CRM, et al. Among authors: willemse m. Mol Ther Methods Clin Dev. 2019 Sep 12;15:120-132. doi: 10.1016/j.omtm.2019.09.002. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31649961 Free PMC article.

7

Block or degrade? Balancing on- and off-target effects of antisense strategies against transcripts with expanded triplet repeats in DM1.

El Boujnouni N, van der Bent ML, Willemse M, 't Hoen PAC, Brock R, Wansink DG. El Boujnouni N, et al. Among authors: willemse m. Mol Ther Nucleic Acids. 2023 Apr 20;32:622-636. doi: 10.1016/j.omtn.2023.04.010. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37200862 Free PMC article.

8

Cancer cell metabolism regulates extracellular matrix degradation by invadopodia.

van Horssen R, Buccione R, Willemse M, Cingir S, Wieringa B, Attanasio F. van Horssen R, et al. Among authors: willemse m. Eur J Cell Biol. 2013 Mar;92(3):113-21. doi: 10.1016/j.ejcb.2012.11.003. Epub 2013 Jan 8. Eur J Cell Biol. 2013. PMID: 23306026

9

The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation.

de Bruijn DR, Allander SV, van Dijk AH, Willemse MP, Thijssen J, van Groningen JJ, Meltzer PS, van Kessel AG. de Bruijn DR, et al. Among authors: willemse mp. Cancer Res. 2006 Oct 1;66(19):9474-82. doi: 10.1158/0008-5472.CAN-05-3726. Cancer Res. 2006. PMID: 17018603

10

Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.

de Groof AJ, te Lindert MM, van Dommelen MM, Wu M, Willemse M, Smift AL, Winer M, Oerlemans F, Pluk H, Fransen JA, Wieringa B. de Groof AJ, et al. Among authors: willemse m. Mol Cancer. 2009 Jul 31;8:54. doi: 10.1186/1476-4598-8-54. Mol Cancer. 2009. PMID: 19646236 Free PMC article.

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