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Page 1
Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy.
Baldwin JG, Heuser-Loy C, Saha T, Schelker RC, Slavkovic-Lukic D, Strieder N, Hernandez-Lopez I, Rana N, Barden M, Mastrogiovanni F, Martín-Santos A, Raimondi A, Brohawn P, Higgs BW, Gebhard C, Kapoor V, Telford WG, Gautam S, Xydia M, Beckhove P, Frischholz S, Schober K, Kontarakis Z, Corn JE, Iannacone M, Inverso D, Rehli M, Fioravanti J, Sengupta S, Gattinoni L. Baldwin JG, et al. Among authors: gebhard c. Cell. 2024 Nov 14;187(23):6614-6630.e21. doi: 10.1016/j.cell.2024.08.029. Epub 2024 Sep 13. Cell. 2024. PMID: 39276774 Free article.
LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Schelker RC, Fioravanti J, Mastrogiovanni F, Baldwin JG, Rana N, Li P, Chen P, Vadász T, Spolski R, Heuser-Loy C, Slavkovic-Lukic D, Noronha P, Damiano G, Raccosta L, Maggioni D, Pullugula S, Lin JX, Oh J, Grandinetti P, Lecce M, Hesse L, Kocks E, Martín-Santos A, Gebhard C, Telford WG, Ji Y, Restifo NP, Russo V, Rehli M, Herr W, Leonard WJ, Gattinoni L. Schelker RC, et al. Among authors: gebhard c. Signal Transduct Target Ther. 2024 Aug 9;9(1):199. doi: 10.1038/s41392-024-01915-z. Signal Transduct Target Ther. 2024. PMID: 39117617 Free PMC article.
STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia.
Fischer A, Hernández-Rodríguez B, Mulet-Lazaro R, Nuetzel M, Hölzl F, van Herk S, Kavelaars FG, Stanewsky H, Ackermann U, Niang AH, Diaz N, Reuschel E, Strieder N, Hernández-López I, Valk PJM, Vaquerizas JM, Rehli M, Delwel R, Gebhard C. Fischer A, et al. Among authors: gebhard c. Cell Rep. 2024 Aug 27;43(8):114498. doi: 10.1016/j.celrep.2024.114498. Epub 2024 Jul 30. Cell Rep. 2024. PMID: 39084219 Free article.
C-Jun drives melanoma progression in PTEN wild type melanoma cells.
Kappelmann-Fenzl M, Gebhard C, Matthies AO, Kuphal S, Rehli M, Bosserhoff AK. Kappelmann-Fenzl M, et al. Among authors: gebhard c. Cell Death Dis. 2019 Aug 5;10(8):584. doi: 10.1038/s41419-019-1821-9. Cell Death Dis. 2019. PMID: 31378787 Free PMC article.
Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy.
Bittner S, Ruhland B, Hofmann V, Schmidleithner L, Schambeck K, Pant A, Stüve P, Delacher M, Echtenacher B, Edinger M, Hoffmann P, Rehli M, Gebhard C, Strieder N, Hehlgans T, Feuerer M. Bittner S, et al. Among authors: gebhard c. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2208436119. doi: 10.1073/pnas.2208436119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161919 Free PMC article.
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Sorrentino A, Menevse AN, Michels T, Volpin V, Durst FC, Sax J, Xydia M, Hussein A, Stamova S, Spoerl S, Heuschneider N, Muehlbauer J, Jeltsch KM, Rathinasamy A, Werner-Klein M, Breinig M, Mikietyn D, Kohler C, Poschke I, Purr S, Reidell O, Martins Freire C, Offringa R, Gebhard C, Spang R, Rehli M, Boutros M, Schmidl C, Khandelwal N, Beckhove P. Sorrentino A, et al. Among authors: gebhard c. J Immunother Cancer. 2022 May;10(5):e004258. doi: 10.1136/jitc-2021-004258. J Immunother Cancer. 2022. PMID: 35606086 Free PMC article.
Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host disease.
Dittmar DJ, Pielmeier F, Strieder N, Fischer A, Herbst M, Stanewsky H, Wenzl N, Röseler E, Eder R, Gebhard C, Schwarzfischer-Pfeilschifter L, Albrecht C, Herr W, Edinger M, Hoffmann P, Rehli M. Dittmar DJ, et al. Among authors: gebhard c. Nat Commun. 2024 Apr 15;15(1):3224. doi: 10.1038/s41467-024-47575-z. Nat Commun. 2024. PMID: 38622133 Free PMC article.
281 results