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Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.
Kong AM, Horan KA, Sriratana A, Bailey CG, Collyer LJ, Nandurkar HH, Shisheva A, Layton MJ, Rasko JE, Rowe T, Mitchell CA. Kong AM, et al. Mol Cell Biol. 2006 Aug;26(16):6065-81. doi: 10.1128/MCB.00203-06. Mol Cell Biol. 2006. PMID: 16880518 Free PMC article.
Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes.
Balamatsias D, Kong AM, Waters JE, Sriratana A, Gurung R, Bailey CG, Rasko JE, Tiganis T, Macaulay SL, Mitchell CA. Balamatsias D, et al. Among authors: kong am. J Biol Chem. 2011 Dec 16;286(50):43229-40. doi: 10.1074/jbc.M111.306621. Epub 2011 Oct 15. J Biol Chem. 2011. PMID: 22002247 Free PMC article.
61 results