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Page 1
Identification of Dual Inhibitors Targeting Main Protease (Mpro) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents.
Previti S, Ettari R, Calcaterra E, Roggia M, Natale B, Weldert AC, Müller-Ruttloff C, Salisch F, Irto A, Cigala RM, Ziebuhr J, Schirmeister T, Cosconati S, Zappalà M. Previti S, et al. Among authors: natale b. ACS Med Chem Lett. 2024 Mar 1;15(5):602-609. doi: 10.1021/acsmedchemlett.3c00562. eCollection 2024 May 9. ACS Med Chem Lett. 2024. PMID: 38746883
Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites.
Trotta AM, Tomassi S, Di Maiolo G, Ieranò C, Vetrei C, D'Alterio C, Merlino F, Messere A, D'Aniello A, Del Bene A, Mazzarella V, Roggia M, Natale B, Cutolo R, Campagna E, Mottola S, Russo R, Chambery A, Benedetti R, Altucci L, Cosconati S, Scala S, Di Maro S. Trotta AM, et al. Among authors: natale b. Eur J Med Chem. 2024 Oct 5;276:116669. doi: 10.1016/j.ejmech.2024.116669. Epub 2024 Jul 14. Eur J Med Chem. 2024. PMID: 39053189
Comprehensive structural investigation of a potent and selective CXCR4 antagonist via crosslink modification.
Trotta AM, Mazzarella V, Roggia M, D'Aniello A, Del Bene A, Vetrei C, Di Maiolo G, Campagna E, Natale B, Rea G, Santagata S, D'Alterio C, Cutolo R, Mottola S, Merlino F, Benedetti R, Altucci L, Messere A, Cosconati S, Tomassi S, Scala S, Di Maro S. Trotta AM, et al. Among authors: natale b. Eur J Med Chem. 2024 Dec 5;279:116911. doi: 10.1016/j.ejmech.2024.116911. Epub 2024 Sep 25. Eur J Med Chem. 2024. PMID: 39348763
Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer.
Tomassi S, Natale B, Roggia M, Amato L, De Rosa C, Della Corte CM, Baglini E, Amendola G, Messere A, Di Maro S, Barresi E, Da Settimo F, Trincavelli ML, Ciardiello F, Taliani S, Morgillo F, Cosconati S. Tomassi S, et al. Among authors: natale b. RSC Med Chem. 2024 Oct 3. doi: 10.1039/d4md00553h. Online ahead of print. RSC Med Chem. 2024. PMID: 39512947 Free PMC article.
Pursuing Polypharmacology: Benzothiopyranoindoles as G-Quadruplex Stabilizers and Topoisomerase I Inhibitors for Effective Anticancer Strategies.
Salerno S, Barresi E, Roggia M, Natale B, Marzano S, Hyeraci M, Reina SCR, Baglini E, Amato J, Salvati E, Dalla Via L, Da Settimo F, Cosconati S, Taliani S. Salerno S, et al. Among authors: natale b. ACS Med Chem Lett. 2024 Oct 2;15(11):1875-1883. doi: 10.1021/acsmedchemlett.4c00313. eCollection 2024 Nov 14. ACS Med Chem Lett. 2024. PMID: 39563818
Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity.
Poggetti V, Angeloni E, Germelli L, Natale B, Waqas M, Sarno G, Angeli A, Daniele S, Salerno S, Barresi E, Cosconati S, Castellano S, Da Pozzo E, Costa B, Supuran CT, Da Settimo F, Taliani S. Poggetti V, et al. Among authors: natale b. ACS Chem Neurosci. 2025 Jan 1;16(1):1-15. doi: 10.1021/acschemneuro.4c00477. Epub 2024 Nov 15. ACS Chem Neurosci. 2025. PMID: 39545683
100 results