Stratton MM - Search Results

1

Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.

Narayanan D, Larsen ASG, Gauger SJ, Adafia R, Hammershøi RB, Hamborg L, Bruus-Jensen J, Griem-Krey N, Gee CL, Frølund B, Stratton MM, Kuriyan J, Kastrup JS, Langkilde AE, Wellendorph P, Solbak SMØ. Narayanan D, et al. Among authors: stratton mm. Protein Sci. 2024 Oct;33(10):e5152. doi: 10.1002/pro.5152. Protein Sci. 2024. PMID: 39275999 Free PMC article.

2

A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme.

Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J. Chao LH, et al. Among authors: stratton mm. Cell. 2011 Sep 2;146(5):732-45. doi: 10.1016/j.cell.2011.07.038. Cell. 2011. PMID: 21884935 Free PMC article.

3

Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II.

Stratton MM, Chao LH, Schulman H, Kuriyan J. Stratton MM, et al. Curr Opin Struct Biol. 2013 Apr;23(2):292-301. doi: 10.1016/j.sbi.2013.04.002. Epub 2013 Apr 27. Curr Opin Struct Biol. 2013. PMID: 23632248 Free PMC article. Review.

4

Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity.

Stratton M, Lee IH, Bhattacharyya M, Christensen SM, Chao LH, Schulman H, Groves JT, Kuriyan J. Stratton M, et al. Elife. 2014 Jan 28;3:e01610. doi: 10.7554/eLife.01610. Elife. 2014. PMID: 24473075 Free PMC article.

5

Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.

Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J. Bhattacharyya M, et al. Among authors: stratton mm. Elife. 2016 Mar 7;5:e13405. doi: 10.7554/eLife.13405. Elife. 2016. PMID: 26949248 Free PMC article.

6

Characterization of CaMKIIα holoenzyme stability.

Torres-Ocampo AP, Özden C, Hommer A, Gardella A, Lapinskas E, Samkutty A, Esposito E, Garman SC, Stratton MM. Torres-Ocampo AP, et al. Among authors: stratton mm. Protein Sci. 2020 Jun;29(6):1524-1534. doi: 10.1002/pro.3869. Epub 2020 May 2. Protein Sci. 2020. PMID: 32282091 Free PMC article.

7

Functional implications of CaMKII alternative splicing.

Sloutsky R, Stratton MM. Sloutsky R, et al. Among authors: stratton mm. Eur J Neurosci. 2021 Oct;54(8):6780-6794. doi: 10.1111/ejn.14761. Epub 2020 May 26. Eur J Neurosci. 2021. PMID: 32343011 Free PMC article. Review.

8

Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation.

Sloutsky R, Dziedzic N, Dunn MJ, Bates RM, Torres-Ocampo AP, Boopathy S, Page B, Weeks JG, Chao LH, Stratton MM. Sloutsky R, et al. Among authors: stratton mm. Sci Signal. 2020 Jul 21;13(641):eaaz0240. doi: 10.1126/scisignal.aaz0240. Sci Signal. 2020. PMID: 32694170 Free PMC article.

9

CaMKII binds both substrates and activators at the active site.

Özden C, Sloutsky R, Mitsugi T, Santos N, Agnello E, Gaubitz C, Foster J, Lapinskas E, Esposito EA, Saneyoshi T, Kelch BA, Garman SC, Hayashi Y, Stratton MM. Özden C, et al. Among authors: stratton mm. Cell Rep. 2022 Jul 12;40(2):111064. doi: 10.1016/j.celrep.2022.111064. Cell Rep. 2022. PMID: 35830796 Free PMC article.

10

Start spreading the news! CaMKII shares activity with naive molecules.

Stratton MM. Stratton MM. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2216529119. doi: 10.1073/pnas.2216529119. Epub 2022 Nov 30. Proc Natl Acad Sci U S A. 2022. PMID: 36449548 Free PMC article. No abstract available.

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