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Page 1
NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.
Rodriguez-Flores JL, Khalid S, Parikshak N, Rasheed A, Ye B, Kapoor M, Backman J, Sepehrband F, Gioia SAD, Gelfman S, De T, Banerjee N, Sharma D, Martinez H, Castaneda S, D'Ambrosio D, Zhang XA, Xun P, Tsai E, Tsai IC; Regeneron Genetics Center; Khan MZ, Jahanzaib M, Mian MR, Liaqat MB, Mahmood K, Salam TU, Hussain M, Iqbal J, Aslam F, Cantor MN, Tzoneva G, Overton J, Marchini J, Reid JG, Baras A, Verweij N, Lotta LA, Coppola G, Karalis K, Economides A, Fazio S, Liedtke W, Danesh J, Kamal A, Frossard P, Coleman T, Shuldiner AR, Saleheen D. Rodriguez-Flores JL, et al. Among authors: danesh j. Nat Commun. 2024 Sep 13;15(1):8029. doi: 10.1038/s41467-024-51819-3. Nat Commun. 2024. PMID: 39271666 Free PMC article.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, De Borst MH, Polašek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poulter N, … See abstract for full author list ➔ Keaton JM, et al. Among authors: danesh jn. Nat Genet. 2024 May;56(5):778-791. doi: 10.1038/s41588-024-01714-w. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689001 Free PMC article.
Rare and common genetic determinants of metabolic individuality and their effects on human health.
Surendran P, Stewart ID, Au Yeung VPW, Pietzner M, Raffler J, Wörheide MA, Li C, Smith RF, Wittemans LBL, Bomba L, Menni C, Zierer J, Rossi N, Sheridan PA, Watkins NA, Mangino M, Hysi PG, Di Angelantonio E, Falchi M, Spector TD, Soranzo N, Michelotti GA, Arlt W, Lotta LA, Denaxas S, Hemingway H, Gamazon ER, Howson JMM, Wood AM, Danesh J, Wareham NJ, Kastenmüller G, Fauman EB, Suhre K, Butterworth AS, Langenberg C. Surendran P, et al. Among authors: danesh j. Nat Med. 2022 Nov;28(11):2321-2332. doi: 10.1038/s41591-022-02046-0. Epub 2022 Nov 10. Nat Med. 2022. PMID: 36357675 Free PMC article.
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.
Emerging Risk Factors Collaboration; Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, Danesh J. Emerging Risk Factors Collaboration, et al. Among authors: danesh j. Lancet. 2010 Jan 9;375(9709):132-40. doi: 10.1016/S0140-6736(09)61717-7. Epub 2009 Dec 22. Lancet. 2010. PMID: 20031199 Free PMC article.
Leucocyte telomere length and conduction system ageing.
van Duijvenboden S, Nelson CP, Raisi-Estabragh Z, Ramirez J, Orini M, Wang Q, Aung N, Codd V, Stoma S, Allara E, Wood AM, Di Angelantonio E, Danesh J, Harvey NC, Petersen SE, Munroe PB, Samani NJ. van Duijvenboden S, et al. Among authors: danesh j. Heart. 2024 Dec 17:heartjnl-2024-324875. doi: 10.1136/heartjnl-2024-324875. Online ahead of print. Heart. 2024. PMID: 39689933 Free article.
Novel loci and biomedical consequences of iron homoeostasis variation.
Allara E, Bell S, Smith R, Keene SJ, Gill D, Gaziano L, Morselli Gysi D, Wang F, Tragante V, Mason A, Karthikeyan S, Lumbers RT, Bonglack E, Ouwehand W, Roberts DJ, Dowsett J, Ostrowski SR, Larsen MH, Ullum H, Pedersen OB, Brunak S, Banasik K, Erikstrup C; DBDS Genomic Consortium; Mitchell J, Fuchsberger C, Pattaro C, Pramstaller PP, Girelli D, Arvas M, Toivonen J, Molnos S, Peters A, Polasek O, Rudan I, Hayward C, McDonnell C, Pirastu N, Wilson JF, van den Hurk K, Quee F, Ferrucci L, Bandinelli S, Tanaka T, Girotto G, Concas MP, Pecori A, Verweij N, van der Harst P, van de Vegte YJ, Kiemeney LA, Sweep FC, Galesloot TE, Sulem P, Gudbjartsson D, Ferkingstad E; FinnGen Consortium; Djousse L, Cho K, Inouye M, Burgess S, Benyamin B, Oexle K, Swinkels D, Stefansson K, Magnusson M, Ganna A, Gaziano M, Ivey K, Danesh J, Pereira A, Wood AM, Butterworth AS, Di Angelantonio E. Allara E, et al. Among authors: danesh j. Commun Biol. 2024 Dec 6;7(1):1631. doi: 10.1038/s42003-024-07115-3. Commun Biol. 2024. PMID: 39643614 Free PMC article.
Preoperative Routine Cold-water Immersion for Lipedema Reduction Surgery.
Schwartz JS, Danesh E, Danesh N, Raghebi A, Danesh J, West J. Schwartz JS, et al. Among authors: danesh j. Plast Reconstr Surg Glob Open. 2024 Dec 5;12(12):e6367. doi: 10.1097/GOX.0000000000006367. eCollection 2024 Dec. Plast Reconstr Surg Glob Open. 2024. PMID: 39640214 Free PMC article.
Nutritional quality of diet characterized by the Nutri-Score profiling system and cardiovascular disease risk: a prospective study in 7 European countries.
Deschasaux-Tanguy M, Huybrechts I, Julia C, Hercberg S, Sarda B, Fialon M, Arnault N, Srour B, Kesse-Guyot E, Fezeu LK, Biessy C, Casagrande C, Hemon B, Weiderpass E, Pinho MGM, Murphy N, Freisling H, Ferrari P, Tjønneland A, Nielsen Petersen KE, Katzke V, Kaaks R, Schulze MB, Masala G, Pala V, Panico S, Ricceri F, Verschuren WMM, Boer JMA, van der Schouw YT, Skeie G, Agudo A, Molina-Montes E, Huerta JM, Moreno-Iribas C, Ericson U, Sonestedt E, Strid A, Oskarsson V, Tong TYN, Heath AK, Aglago EK, Danesh J, Riboli E, Gunter MJ, Touvier M. Deschasaux-Tanguy M, et al. Among authors: danesh j. Lancet Reg Health Eur. 2024 Sep 10;46:101006. doi: 10.1016/j.lanepe.2024.101006. eCollection 2024 Nov. Lancet Reg Health Eur. 2024. PMID: 39529812 Free PMC article.
Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records.
Fletcher RA, Rockenschaub P, Neuen BL, Walter IJ, Conrad N, Mizani MA, Bolton T, Lawson CA, Tomlinson C, Logothetis SB, Petitjean C, Brizzi LF, Kaptoge S, Raffetti E, Calvert PA, Di Angelantonio E, Banerjee A, Mamas MA, Squire I, Denaxas S, McDonagh TA, Sudlow C, Petersen SE, Chertow GM, Khunti K, Sundström J, Arnott C, Cleland JGF, Danesh J, McMurray JJV, Vaduganathan M, Wood AM; CVD-COVID-UK/COVID-IMPACT Consortium. Fletcher RA, et al. Among authors: danesh j. Lancet Public Health. 2024 Nov;9(11):e871-e885. doi: 10.1016/S2468-2667(24)00215-9. Lancet Public Health. 2024. PMID: 39486903 Free article.
Association of circulating fatty acids with cardiovascular disease risk: Analysis of individual-level data in three large prospective cohorts and updated meta-analysis.
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, Steur M, Aleksandrova K, Dahm CC, Schulze MB, van der Schouw YT, Agnoli C, Amiano P, Boer JMA, Bork CS, Cabrera-Castro N, Eichelmann F, Elbaz A, Farràs M, Heath AK, Kaaks R, Katzke V, Keski-Rahkonen P, Masala G, Moreno-Iribas C, Panico S, Papier K, Petrova D, Quirós JR, Ricceri F, Severi G, Tjønneland A, Tong TYN, Tumino R, Wareham N, Weiderpass E, Di Angelantonio E, Forouhi N, Danesh J, Butterworth AS, Kaptoge S. Shi F, et al. Among authors: danesh j. Eur J Prev Cardiol. 2024 Oct 4:zwae315. doi: 10.1093/eurjpc/zwae315. Online ahead of print. Eur J Prev Cardiol. 2024. PMID: 39365172
448 results