Giralt A - Search Results

1

RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer's disease.

Campoy-Campos G, Solana-Balaguer J, Guisado-Corcoll A, Chicote-González A, Garcia-Segura P, Pérez-Sisqués L, Torres AG, Canal M, Molina-Porcel L, Fernández-Irigoyen J, Santamaria E, Ribas de Pouplana L, Alberch J, Martí E, Giralt A, Pérez-Navarro E, Malagelada C. Campoy-Campos G, et al. Among authors: giralt a. Nucleic Acids Res. 2024 Oct 14;52(18):11158-11176. doi: 10.1093/nar/gkae776. Nucleic Acids Res. 2024. PMID: 39268577 Free PMC article.

2

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling.

Torres-Peraza JF, Giralt A, García-Martínez JM, Pedrosa E, Canals JM, Alberch J. Torres-Peraza JF, et al. Among authors: giralt a. Neurobiol Dis. 2008 Mar;29(3):409-21. doi: 10.1016/j.nbd.2007.10.003. Epub 2007 Oct 23. Neurobiol Dis. 2008. PMID: 18063376 Free article.

3

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression.

Giralt A, Rodrigo T, Martín ED, Gonzalez JR, Milà M, Ceña V, Dierssen M, Canals JM, Alberch J. Giralt A, et al. Neuroscience. 2009 Feb 18;158(4):1234-50. doi: 10.1016/j.neuroscience.2008.11.024. Epub 2008 Nov 21. Neuroscience. 2009. PMID: 19121372

4

Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study.

Sabater L, Giralt A, Boronat A, Hankiewicz K, Blanco Y, Llufriu S, Alberch J, Graus F, Saiz A. Sabater L, et al. Among authors: giralt a. J Neuroimmunol. 2009 Oct 30;215(1-2):31-5. doi: 10.1016/j.jneuroim.2009.07.014. Epub 2009 Aug 19. J Neuroimmunol. 2009. PMID: 19695715

5

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Xifró X, Giralt A, Saavedra A, García-Martínez JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Xifró X, et al. Among authors: giralt a. Neurobiol Dis. 2009 Dec;36(3):461-9. doi: 10.1016/j.nbd.2009.08.012. Epub 2009 Sep 4. Neurobiol Dis. 2009. PMID: 19733666

6

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. Among authors: giralt a. Cell Death Differ. 2010 Feb;17(2):324-35. doi: 10.1038/cdd.2009.127. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745829

7

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

Giralt A, Friedman HC, Caneda-Ferrón B, Urbán N, Moreno E, Rubio N, Blanco J, Peterson A, Canals JM, Alberch J. Giralt A, et al. Gene Ther. 2010 Oct;17(10):1294-308. doi: 10.1038/gt.2010.71. Epub 2010 May 13. Gene Ther. 2010. PMID: 20463759

8

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.

Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. Among authors: giralt a. J Neurosci. 2011 Jun 1;31(22):8150-62. doi: 10.1523/JNEUROSCI.3446-10.2011. J Neurosci. 2011. PMID: 21632937 Free PMC article.

9

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.

Giralt A, Saavedra A, Carretón O, Xifró X, Alberch J, Pérez-Navarro E. Giralt A, et al. Hum Mol Genet. 2011 Nov 1;20(21):4232-47. doi: 10.1093/hmg/ddr351. Epub 2011 Aug 11. Hum Mol Genet. 2011. PMID: 21835884

10

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction.

Giralt A, Carretón O, Lao-Peregrin C, Martín ED, Alberch J. Giralt A, et al. Mol Neurodegener. 2011 Oct 10;6(1):71. doi: 10.1186/1750-1326-6-71. Mol Neurodegener. 2011. PMID: 21985529 Free PMC article.

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