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Regression of renal cell carcinoma by T cell receptor-engineered T cells targeting a human endogenous retrovirus.
Barisic S, Brahmbhatt EM, Cherkasova E, Spear TT, Savani U, Pierre S, Scurti GM, Chen L, Igboko M, Nadal R, Zeng G, Parry G, Stroncek DF, Highfill S, Dalheim AV, Reger R, Nishimura MI, Childs RW. Barisic S, et al. Among authors: highfill s. J Immunother Cancer. 2024 Sep 11;12(9):e009147. doi: 10.1136/jitc-2024-009147. J Immunother Cancer. 2024. PMID: 39266213 Free PMC article.
Deregulated expression of LRBA facilitates cancer cell growth.
Wang JW, Gamsby JJ, Highfill SL, Mora LB, Bloom GC, Yeatman TJ, Pan TC, Ramne AL, Chodosh LA, Cress WD, Chen J, Kerr WG. Wang JW, et al. Oncogene. 2004 May 20;23(23):4089-97. doi: 10.1038/sj.onc.1207567. Oncogene. 2004. PMID: 15064745
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Highfill SL, Rodriguez PC, Zhou Q, Goetz CA, Koehn BH, Veenstra R, Taylor PA, Panoskaltsis-Mortari A, Serody JS, Munn DH, Tolar J, Ochoa AC, Blazar BR. Highfill SL, et al. Blood. 2010 Dec 16;116(25):5738-47. doi: 10.1182/blood-2010-06-287839. Epub 2010 Aug 31. Blood. 2010. PMID: 20807889 Free PMC article.
Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells.
Stroncek DF, Lee DW, Ren J, Sabatino M, Highfill S, Khuu H, Shah NN, Kaplan RN, Fry TJ, Mackall CL. Stroncek DF, et al. Among authors: highfill s. J Transl Med. 2017 Mar 16;15(1):59. doi: 10.1186/s12967-017-1160-5. J Transl Med. 2017. PMID: 28298232 Free PMC article. Clinical Trial.
A Phase 1 trial of autologous monocytes stimulated ex vivo with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for intra-peritoneal administration in recurrent ovarian cancer.
Green DS, Nunes AT, David-Ocampo V, Ekwede IB, Houston ND, Highfill SL, Khuu H, Stroncek DF, Steinberg SM, Zoon KC, Annunziata CM. Green DS, et al. Among authors: highfill sl. J Transl Med. 2018 Jul 16;16(1):196. doi: 10.1186/s12967-018-1569-5. J Transl Med. 2018. PMID: 30012146 Free PMC article. Clinical Trial.
65 results