Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.
Santo-Domingo J, Chareyron I, Dayon L, Núñez Galindo A, Cominetti O, Pilar Giner Giménez M, De Marchi U, Canto C, Kussmann M, Wiederkehr A.
Santo-Domingo J, et al. Among authors: dayon l.
FASEB J. 2017 Mar;31(3):1028-1045. doi: 10.1096/fj.201600837R. Epub 2016 Dec 7.
FASEB J. 2017.
PMID: 27927723
We conclude that non-nutrient secretagogues act, in part, via PKC and downstream ERK1/2 signaling to stimulate mitochondrial energy production to compensate for energy expenditure that is linked to beta-cell activation.-Santo-Domingo, J., Chareyron, I., Dayon, L., G …
We conclude that non-nutrient secretagogues act, in part, via PKC and downstream ERK1/2 signaling to stimulate mitochondrial energy producti …