Sobie EA - Search Results

1

Multiscale mapping of transcriptomic signatures for cardiotoxic drugs.

Hansen J, Xiong Y, Siddiq MM, Dhanan P, Hu B, Shewale B, Yadaw AS, Jayaraman G, Tolentino RE, Chen Y, Martinez P, Beaumont KG, Sebra R, Vidovic D, Schürer SC, Goldfarb J, Gallo JM, Birtwistle MR, Sobie EA, Azeloglu EU, Berger SI, Chan A, Schaniel C, Dubois NC, Iyengar R. Hansen J, et al. Among authors: sobie ea. Nat Commun. 2024 Sep 11;15(1):7968. doi: 10.1038/s41467-024-52145-4. Nat Commun. 2024. PMID: 39261481 Free PMC article.

2

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines.

Niepel M, Hafner M, Mills CE, Subramanian K, Williams EH, Chung M, Gaudio B, Barrette AM, Stern AD, Hu B, Korkola JE; LINCS Consortium; Gray JW, Birtwistle MR, Heiser LM, Sorger PK. Niepel M, et al. Cell Syst. 2019 Jul 24;9(1):35-48.e5. doi: 10.1016/j.cels.2019.06.005. Epub 2019 Jul 10. Cell Syst. 2019. PMID: 31302153 Free PMC article.

3

Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes Towards a Purkinje Fiber Fate.

Gonzalez DM, Dariolli R, Moyett J, Song S, Shewale B, Bliley J, Clarke D, Ma'ayan A, Rentschler S, Feinberg A, Sobie E, Dubois NC. Gonzalez DM, et al. bioRxiv [Preprint]. 2024 Sep 28:2024.09.22.614353. doi: 10.1101/2024.09.22.614353. bioRxiv. 2024. PMID: 39386729 Free PMC article. Preprint.

4

Cell-to-cell heterogeneity in ion channel conductance impacts substrate vulnerability to arrhythmia.

Pullinger TK, Sobie EA. Pullinger TK, et al. Among authors: sobie ea. Am J Physiol Heart Circ Physiol. 2024 Jul 1;327(1):H242-H254. doi: 10.1152/ajpheart.00645.2023. Epub 2024 May 17. Am J Physiol Heart Circ Physiol. 2024. PMID: 38758124

5

Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experiments.

Yang J, Daily NJ, Pullinger TK, Wakatsuki T, Sobie EA. Yang J, et al. Among authors: sobie ea. PLoS Comput Biol. 2024 Sep 11;20(9):e1011806. doi: 10.1371/journal.pcbi.1011806. eCollection 2024 Sep. PLoS Comput Biol. 2024. PMID: 39259757 Free PMC article.

6

HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia.

Rodríguez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodríguez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD. Rodríguez NA, et al. Among authors: sobie ea. Circ Arrhythm Electrophysiol. 2024 Apr;17(4):e012022. doi: 10.1161/CIRCEP.123.012022. Epub 2024 Feb 28. Circ Arrhythm Electrophysiol. 2024. PMID: 38415356

7

Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experiments.

Yang J, Daily N, Pullinger TK, Wakatsuki T, Sobie EA. Yang J, et al. Among authors: sobie ea. bioRxiv [Preprint]. 2024 Jan 8:2024.01.07.574577. doi: 10.1101/2024.01.07.574577. bioRxiv. 2024. Update in: PLoS Comput Biol. 2024 Sep 11;20(9):e1011806. doi: 10.1371/journal.pcbi.1011806 PMID: 38260376 Free PMC article. Updated. Preprint.

8

Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors.

Shim JV, Xiong Y, Dhanan P, Dariolli R, Azeloglu EU, Hu B, Jayaraman G, Schaniel C, Birtwistle MR, Iyengar R, Dubois NC, Sobie EA. Shim JV, et al. Among authors: sobie ea. Front Pharmacol. 2023 Apr 10;14:1158222. doi: 10.3389/fphar.2023.1158222. eCollection 2023. Front Pharmacol. 2023. PMID: 37101545 Free PMC article.

9

Mavacamten improves symptoms in obstructive hypertrophic cardiomyopathy patients.

Zatorski N, Sobie EA, Schlessinger A. Zatorski N, et al. Among authors: sobie ea. Trends Pharmacol Sci. 2023 May;44(5):318-319. doi: 10.1016/j.tips.2023.02.005. Epub 2023 Mar 12. Trends Pharmacol Sci. 2023. PMID: 36914446 Free PMC article.

10

Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models.

Campana C, Ricci E, Bartolucci C, Severi S, Sobie EA. Campana C, et al. Among authors: sobie ea. PLoS Comput Biol. 2022 Nov 21;18(11):e1010098. doi: 10.1371/journal.pcbi.1010098. eCollection 2022 Nov. PLoS Comput Biol. 2022. PMID: 36409762 Free PMC article.

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