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Page 1
Multiscale mapping of transcriptomic signatures for cardiotoxic drugs.
Hansen J, Xiong Y, Siddiq MM, Dhanan P, Hu B, Shewale B, Yadaw AS, Jayaraman G, Tolentino RE, Chen Y, Martinez P, Beaumont KG, Sebra R, Vidovic D, Schürer SC, Goldfarb J, Gallo JM, Birtwistle MR, Sobie EA, Azeloglu EU, Berger SI, Chan A, Schaniel C, Dubois NC, Iyengar R. Hansen J, et al. Among authors: birtwistle mr. Nat Commun. 2024 Sep 11;15(1):7968. doi: 10.1038/s41467-024-52145-4. Nat Commun. 2024. PMID: 39261481 Free PMC article.
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity.
van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, Azeloglu EU, Iyengar R. van Hasselt JGC, et al. Among authors: birtwistle mr. Nat Commun. 2020 Sep 23;11(1):4809. doi: 10.1038/s41467-020-18396-7. Nat Commun. 2020. PMID: 32968055 Free PMC article.
Protein structure-based gene expression signatures.
Rahman R, Zatorski N, Hansen J, Xiong Y, van Hasselt JGC, Sobie EA, Birtwistle MR, Azeloglu EU, Iyengar R, Schlessinger A. Rahman R, et al. Among authors: birtwistle mr. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2014866118. doi: 10.1073/pnas.2014866118. Proc Natl Acad Sci U S A. 2021. PMID: 33941686 Free PMC article.
A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals.
Schaniel C, Dhanan P, Hu B, Xiong Y, Raghunandan T, Gonzalez DM, Dariolli R, D'Souza SL, Yadaw AS, Hansen J, Jayaraman G, Mathew B, Machado M, Berger SI, Tripodi J, Najfeld V, Garg J, Miller M, Surlyn CS, Michelis KC, Tangirala NC, Weerahandi H, Thomas DC, Beaumont KG, Sebra R, Mahajan M, Schadt E, Vidovic D, Schürer SC, Goldfarb J, Azeloglu EU, Birtwistle MR, Sobie EA, Kovacic JC, Dubois NC, Iyengar R. Schaniel C, et al. Among authors: birtwistle mr. Stem Cell Reports. 2021 Dec 14;16(12):3036-3049. doi: 10.1016/j.stemcr.2021.10.005. Epub 2021 Nov 4. Stem Cell Reports. 2021. PMID: 34739849 Free PMC article.
Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity.
Xiong Y, Liu T, Chen T, Hansen J, Hu B, Chen Y, Jayaraman G, Schürer S, Vidovic D, Goldfarb J, Sobie EA, Birtwistle MR, Iyengar R, Li H, Azeloglu EU. Xiong Y, et al. Among authors: birtwistle mr. Sci Data. 2022 Jan 20;9(1):18. doi: 10.1038/s41597-021-01114-3. Sci Data. 2022. PMID: 35058449 Free PMC article.
A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.
Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR. Xiong Y, et al. Among authors: birtwistle mr. Sci Rep. 2017 Nov 7;7(1):14626. doi: 10.1038/s41598-017-14892-x. Sci Rep. 2017. PMID: 29116112 Free PMC article.
Wilm's tumor 1 promotes memory flexibility.
Mariottini C, Munari L, Gunzel E, Seco JM, Tzavaras N, Hansen J, Stern SA, Gao V, Aleyasin H, Sharma A, Azeloglu EU, Hodes GE, Russo SJ, Huff V, Birtwistle MR, Blitzer RD, Alberini CM, Iyengar R. Mariottini C, et al. Among authors: birtwistle mr. Nat Commun. 2019 Aug 21;10(1):3756. doi: 10.1038/s41467-019-11781-x. Nat Commun. 2019. PMID: 31434897 Free PMC article.
Network pharmacodynamic models for customized cancer therapy.
Gallo JM, Birtwistle MR. Gallo JM, et al. Among authors: birtwistle mr. Wiley Interdiscip Rev Syst Biol Med. 2015 Jul-Aug;7(4):243-51. doi: 10.1002/wsbm.1300. Epub 2015 Apr 24. Wiley Interdiscip Rev Syst Biol Med. 2015. PMID: 25914386 Free PMC article.
78 results