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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Peng JY, Sprenger B, He X, Moghadasi SA, Egger LM, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Dunzendorfer-Matt T, Naschberger A, Wang D, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: harris rs. PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39259728 Free PMC article.
SARS-CoV-2 Mpro inhibitor identification using a cellular gain-of-signal assay for high-throughput screening.
Delgado R, Vishwakarma J, Moghadasi SA, Otsuka Y, Shumate J, Cuell A, Tansiongco M, Cooley CB, Chen Y, Dabrowska A, Basu R, Anindita PD, Luo D, Dosa PI, Harki DA, Bannister T, Scampavia L, Spicer TP, Harris RS. Delgado R, et al. Among authors: harris rs. SLAS Discov. 2024 Sep;29(6):100181. doi: 10.1016/j.slasd.2024.100181. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173830 Free PMC article.
Regulatory interactions between APOBEC3B N- and C-terminal domains.
Braza MKE, Demir Ö, Ahn SH, Morris CK, Calvó-Tusell C, McGuire KL, de la Peña Avalos B, Carpenter MA, Chen Y, Casalino L, Aihara H, Herzik MA, Harris RS, Amaro RE. Braza MKE, et al. Among authors: harris rs. bioRxiv [Preprint]. 2024 Dec 12:2024.12.11.628032. doi: 10.1101/2024.12.11.628032. bioRxiv. 2024. PMID: 39713448 Free PMC article. Preprint.
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma.
Smith NJ, Reddin I, Policelli P, Oh S, Zainal N, Howes E, Jenkins B, Tracy I, Edmond M, Sharpe B, Amendra D, Zheng K, Egawa N, Doorbar J, Rao A, Mahadevan S, Carpenter MA, Harris RS, Ali S, Hanley C, Buisson R, King E, Thomas GJ, Fenton TR. Smith NJ, et al. Among authors: harris rs. EMBO J. 2024 Nov 15. doi: 10.1038/s44318-024-00298-9. Online ahead of print. EMBO J. 2024. PMID: 39548236 Free article.
RADD: A real-time FRET-based biochemical assay for DNA deaminase studies.
Belica CA, Hernandez PC, Carpenter MA, Chen Y, Brown WL, Harris RS, Aihara H. Belica CA, et al. Among authors: harris rs. Methods Enzymol. 2024;705:311-345. doi: 10.1016/bs.mie.2024.08.001. Epub 2024 Aug 27. Methods Enzymol. 2024. PMID: 39389668 Free PMC article.
Complete sequencing of ape genomes.
Yoo D, Rhie A, Hebbar P, Antonacci F, Logsdon GA, Solar SJ, Antipov D, Pickett BD, Safonova Y, Montinaro F, Luo Y, Malukiewicz J, Storer JM, Lin J, Sequeira AN, Mangan RJ, Hickey G, Anez GM, Balachandran P, Bankevich A, Beck CR, Biddanda A, Borchers M, Bouffard GG, Brannan E, Brooks SY, Carbone L, Carrel L, Chan AP, Crawford J, Diekhans M, Engelbrecht E, Feschotte C, Formenti G, Garcia GH, de Gennaro L, Gilbert D, Green RE, Guarracino A, Gupta I, Haddad D, Han J, Harris RS, Hartley GA, Harvey WT, Hiller M, Hoekzema K, Houck ML, Jeong H, Kamali K, Kellis M, Kille B, Lee C, Lee Y, Lees W, Lewis AP, Li Q, Loftus M, Loh YHE, Loucks H, Ma J, Mao Y, Martinez JFI, Masterson P, McCoy RC, McGrath B, McKinney S, Meyer BS, Miga KH, Mohanty SK, Munson KM, Pal K, Pennell M, Pevzner PA, Porubsky D, Potapova T, Ringeling FR, Roha JL, Ryder OA, Sacco S, Saha S, Sasaki T, Schatz MC, Schork NJ, Shanks C, Smeds L, Son DR, Steiner C, Sweeten AP, Tassia MG, Thibaud-Nissen F, Torres-González E, Trivedi M, Wei W, Wertz J, Yang M, Zhang P, Zhang S, Zhang Y, Zhang Z, Zhao SA, Zhu Y, Jarvis ED, Gerton JL, Rivas-González I, Paten B, Szpiech ZA, Huber CD, Lenz TL, Konkel MK, Yi SV, Canzar S, Watson CT… See abstract for full author list ➔ Yoo D, et al. Among authors: harris rs. bioRxiv [Preprint]. 2024 Oct 5:2024.07.31.605654. doi: 10.1101/2024.07.31.605654. bioRxiv. 2024. PMID: 39131277 Free PMC article. Preprint.
527 results