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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Peng JY, Sprenger B, He X, Moghadasi SA, Egger LM, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Dunzendorfer-Matt T, Naschberger A, Wang D, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: fleischmann j. PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39259728 Free PMC article.
A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Sprenger B, Moghadasi SA, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: fleischmann j. bioRxiv [Preprint]. 2023 Oct 4:2023.09.22.558628. doi: 10.1101/2023.09.22.558628. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522 PMID: 37808638 Free PMC article. Updated. Preprint.
Impact of protein and small molecule interactions on kinase conformations.
Kugler V, Schwaighofer S, Feichtner A, Enzler F, Fleischmann J, Strich S, Schwarz S, Wilson R, Tschaikner P, Troppmair J, Sexl V, Meier P, Kaserer T, Stefan E. Kugler V, et al. Among authors: fleischmann j. Elife. 2024 Aug 1;13:RP94755. doi: 10.7554/eLife.94755. Elife. 2024. PMID: 39088265 Free PMC article.
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Among authors: fleischmann j. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.
Effect of Circular Stapler Diameter on Anastomotic Leakage Rate and Stenosis After Open Total Gastrectomy With Esophagojejunostomy: A Substantive Retrospective Propensity Score Matched Series.
Mittelstädt A, Reitberger H, Fleischmann J, Elshafei M, Brunner M, Anthuber A, Krautz C, Lucio M, Merkel S, Grützmann R, Weber GF. Mittelstädt A, et al. Among authors: fleischmann j. Ann Surg Open. 2022 Sep 7;3(3):e195. doi: 10.1097/AS9.0000000000000195. eCollection 2022 Sep. Ann Surg Open. 2022. PMID: 37601147 Free PMC article.
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