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Page 1
Mitochondrial RNA cytosolic leakage drives the SASP.
Victorelli S, Eppard M, Woo SH, Everts SPA, Martini H, Pirius N, Franco AC, Han Y, Saul D, Splinter PL, O'Hara SP, Valenzuela-Pérez L, Lee HSK, Jurk D, LaRusso NF, Hirsova P, Passos JF. Victorelli S, et al. Among authors: hirsova p. Res Sq [Preprint]. 2024 Aug 27:rs.3.rs-4876596. doi: 10.21203/rs.3.rs-4876596/v1. Res Sq. 2024. PMID: 39257994 Free PMC article. Preprint.
Do autoantigens drive MASH progression?
Valenzuela-Pérez L, Kim Lee HS, Hirsova P. Valenzuela-Pérez L, et al. Among authors: hirsova p. Hepatology. 2024 Aug 5. doi: 10.1097/HEP.0000000000001048. Online ahead of print. Hepatology. 2024. PMID: 39106204 No abstract available.
Glycogen synthase kinase 3 activity enhances liver inflammation in MASH.
Khoury M, Guo Q, Furuta K, Correia C, Meroueh C, Kim Lee HS, Warasnhe K, Valenzuela-Pérez L, Mazar AP, Kim I, Noh YK, Holmes H, Romero MF, Sussman CR, Pavelko KD, Islam S, Bamidele AO, Hirsova P, Li H, Ibrahim SH. Khoury M, et al. Among authors: hirsova p. JHEP Rep. 2024 Mar 26;6(6):101073. doi: 10.1016/j.jhepr.2024.101073. eCollection 2024 Jun. JHEP Rep. 2024. PMID: 38882600 Free PMC article.
Interleukin 21 Drives a Hypermetabolic State and CD4+ T-Cell-Associated Pathogenicity in Chronic Intestinal Inflammation.
Bamidele AO, Mishra SK, Piovezani Ramos G, Hirsova P, Klatt EE, Abdelrahman LM, Sagstetter MR, Davidson HM, Fehrenbach PJ, Valenzuela-Pérez L, Kim Lee HS, Zhang S, Aguirre Lopez A, Kurdi AT, Westphal MS, Gonzalez MM, Gaballa JM, Kosinsky RL, Lee HE, Smyrk TC, Bantug G, Gades NM, Faubion WA Jr. Bamidele AO, et al. Among authors: hirsova p. Gastroenterology. 2024 May;166(5):826-841.e19. doi: 10.1053/j.gastro.2024.01.026. Epub 2024 Jan 23. Gastroenterology. 2024. PMID: 38266738
Macrophage RAGE activation is proinflammatory in NASH.
Parthasarathy G, Mauer AS, Golla N, Daniel PV, Kim LH, Sidhu GS, Marek GW 3rd, Loeuillard E, Krishnan A, Lee HSK, Pavelko KD, Charlton M, Hirsova P, Ilyas SI, Malhi H. Parthasarathy G, et al. Among authors: hirsova p. JCI Insight. 2024 Feb 8;9(3):e169138. doi: 10.1172/jci.insight.169138. JCI Insight. 2024. PMID: 38175729 Free PMC article.
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis.
Lastuvkova H, Nova Z, Hroch M, Alaei Faradonbeh F, Schreiberova J, Mokry J, Faistova H, Stefela A, Dusek J, Kucera O, Hyspler R, Dohnalkova E, Bayer RL, Hirsova P, Pavek P, Micuda S. Lastuvkova H, et al. Among authors: hirsova p. Toxicol Sci. 2023 Nov 28;196(2):200-217. doi: 10.1093/toxsci/kfad088. Toxicol Sci. 2023. PMID: 37632784 Free PMC article.
Extracellular Vesicles in Hepatobiliary Health and Disease.
Parthasarathy G, Hirsova P, Kostallari E, Sidhu GS, Ibrahim SH, Malhi H. Parthasarathy G, et al. Among authors: hirsova p. Compr Physiol. 2023 Jun 26;13(3):4631-4658. doi: 10.1002/cphy.c210046. Compr Physiol. 2023. PMID: 37358519 Free PMC article. Review.
Interleukin-21 Drives a Hypermetabolic State and CD4+ T Cell-associated Pathogenicity in Chronic Intestinal Inflammation.
Bamidele AO, Mishra SK, Hirsova P, Fehrenbach PJ, Valenzuela-Pérez L, Lee HSK. Bamidele AO, et al. Among authors: hirsova p. bioRxiv [Preprint]. 2023 Jun 6:2023.06.02.543518. doi: 10.1101/2023.06.02.543518. bioRxiv. 2023. Update in: Gastroenterology. 2024 May;166(5):826-841.e19. doi: 10.1053/j.gastro.2024.01.026 PMID: 37333332 Free PMC article. Updated. Preprint.
Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis.
Dohnalkova E, Bayer RL, Guo Q, Bamidele AO, Kim Lee HS, Valenzuela-Pérez L, Krishnan A, Pavelko KD, Guisot NES, Bunyard P, Kim YB, Ibrahim SH, Gores GJ, Hirsova P. Dohnalkova E, et al. Among authors: hirsova p. Hepatol Commun. 2023 Jun 2;7(6):e0171. doi: 10.1097/HC9.0000000000000171. eCollection 2023 Jun 1. Hepatol Commun. 2023. PMID: 37267252 Free PMC article.
Transcriptomic landscapes of effective and failed liver regeneration in humans.
Starlinger P, Brunnthaler L, McCabe C, Pereyra D, Santol J, Steadman J, Hackl M, Skalicky S, Hackl H, Gronauer R, O'Brien D, Kain R, Hirsova P, Gores GJ, Wang C, Gruenberger T, Smoot RL, Assinger A. Starlinger P, et al. Among authors: hirsova p. JHEP Rep. 2023 Feb 2;5(4):100683. doi: 10.1016/j.jhepr.2023.100683. eCollection 2023 Apr. JHEP Rep. 2023. PMID: 36950091 Free PMC article.
77 results