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KRASG 12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening.
Tapia Contreras C, Falke JD, Seifert DM, Schneider C, Krauß L, Fang X, Müller D, Demirdizen E, Spitzner M, De Oliveira T, Schneeweis C, Gaedcke J, Kaulfuß S, Mirzakhani K, Wollnik B, Conrads K, Beißbarth T, Salinas G, Hügel J, Beyer N, Rheinländer S, Sax U, Wirth M, Conradi LC, Reichert M, Ellenrieder V, Ströbel P, Ghadimi M, Grade M, Saur D, Hessmann E, Schneider G. Tapia Contreras C, et al. Among authors: grade m. Mol Oncol. 2024 Sep 10. doi: 10.1002/1878-0261.13725. Online ahead of print. Mol Oncol. 2024. PMID: 39253995 Free article.
AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer.
Schneeweis C, Diersch S, Hassan Z, Krauß L, Schneider C, Lucarelli D, Falcomatà C, Steiger K, Öllinger R, Krämer OH, Arlt A, Grade M, Schmidt-Supprian M, Hessmann E, Wirth M, Rad R, Reichert M, Saur D, Schneider G. Schneeweis C, et al. Among authors: grade m. Cell Mol Life Sci. 2022 Dec 19;80(1):12. doi: 10.1007/s00018-022-04638-y. Cell Mol Life Sci. 2022. PMID: 36534167 Free PMC article.
A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction.
Schneider C, Hilbert J, Genevaux F, Höfer S, Krauß L, Schicktanz F, Contreras CT, Jansari S, Papargyriou A, Richter T, Alfayomy AM, Falcomatà C, Schneeweis C, Orben F, Öllinger R, Wegwitz F, Boshnakovska A, Rehling P, Müller D, Ströbel P, Ellenrieder V, Conradi L, Hessmann E, Ghadimi M, Grade M, Wirth M, Steiger K, Rad R, Kuster B, Sippl W, Reichert M, Saur D, Schneider G. Schneider C, et al. Among authors: grade m. Adv Sci (Weinh). 2024 Aug;11(31):e2307695. doi: 10.1002/advs.202307695. Epub 2024 Jun 17. Adv Sci (Weinh). 2024. PMID: 38885414 Free PMC article.
Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.
Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, Kitz J, Kaulfuß S, Beißbarth T, Dobbelstein M, Ghadimi M, Grade M, Gaedcke J. Salendo J, et al. Among authors: grade m. Radiother Oncol. 2013 Sep;108(3):451-7. doi: 10.1016/j.radonc.2013.06.032. Epub 2013 Aug 7. Radiother Oncol. 2013. PMID: 23932154
A gene expression signature for chemoradiosensitivity of colorectal cancer cells.
Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf JG, Burfeind P, Becker H, Beissbarth T, Ghadimi BM, Ried T, Grade M. Spitzner M, et al. Among authors: grade m. Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1184-92. doi: 10.1016/j.ijrobp.2010.06.023. Int J Radiat Oncol Biol Phys. 2010. PMID: 20970032 Free PMC article.
Heterogeneity of KRAS Mutation Status in Rectal Cancer.
Jo P, König A, Schirmer M, Kitz J, Conradi LC, Azizian A, Bernhardt M, Wolff HA, Grade M, Ghadimi M, Ströbel P, Schildhaus HU, Gaedcke J. Jo P, et al. Among authors: grade m. PLoS One. 2016 Apr 11;11(4):e0153278. doi: 10.1371/journal.pone.0153278. eCollection 2016. PLoS One. 2016. PMID: 27064574 Free PMC article.
Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.
Emons G, Spitzner M, Reineke S, Möller J, Auslander N, Kramer F, Hu Y, Beissbarth T, Wolff HA, Rave-Fränk M, Heßmann E, Gaedcke J, Ghadimi BM, Johnsen SA, Ried T, Grade M. Emons G, et al. Among authors: grade m. Mol Cancer Res. 2017 Nov;15(11):1481-1490. doi: 10.1158/1541-7786.MCR-17-0205. Epub 2017 Aug 15. Mol Cancer Res. 2017. PMID: 28811361 Free PMC article.
117 results