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Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function.
Watts E, Willison J, Arienti S, Sadiku P, Coelho P, Sanchez-Garcia M, Zhang A, Murphy F, Dickinson R, Mirchandani A, Morrison T, Lewis A, Vermaelen W, Ghesquiere B, Carmeliet P, Mazzone M, Maxwell P, Pugh C, Dockrell D, Whyte M, Walmsley S. Watts E, et al. Among authors: ghesquiere b. Wellcome Open Res. 2024 Sep 2;8:569. doi: 10.12688/wellcomeopenres.19915.2. eCollection 2023. Wellcome Open Res. 2024. PMID: 39257914 Free PMC article.
Ancient genomic linkage couples metabolism with erythroid development.
Preston AE, Frost JN, Badat M, Teh M, Armitage AE, Norfo R, Wideman SK, Hanifi M, White N, Roy N, Ghesquiere B, Babbs C, Kassouf M, Davies J, Hughes JR, Beagrie R, Higgs DR, Drakesmith H. Preston AE, et al. Among authors: ghesquiere b. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558944. doi: 10.1101/2023.09.25.558944. bioRxiv. 2023. PMID: 37808769 Free PMC article. Preprint.
Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models.
Radenkovic S, Budhraja R, Klein-Gunnewiek T, King AT, Bhatia TN, Ligezka AN, Driesen K, Shah R, Ghesquière B, Pandey A, Kasri NN, Sloan SA, Morava E, Kozicz T. Radenkovic S, et al. Among authors: ghesquiere b. Cell Rep. 2024 Mar 26;43(3):113883. doi: 10.1016/j.celrep.2024.113883. Epub 2024 Mar 1. Cell Rep. 2024. PMID: 38430517 Free article.
Glycosphingolipids in congenital disorders of glycosylation (CDG).
Jáñez Pedrayes A, Rymen D, Ghesquière B, Witters P. Jáñez Pedrayes A, et al. Among authors: ghesquiere b. Mol Genet Metab. 2024 May;142(1):108434. doi: 10.1016/j.ymgme.2024.108434. Epub 2024 Mar 5. Mol Genet Metab. 2024. PMID: 38489976 Review.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Sneyers F, Kerkhofs M, Speelman-Rooms F, Welkenhuyzen K, La Rovere R, Shemy A, Voet A, Eelen G, Dewerchin M, Tait SWG, Ghesquière B, Bootman MD, Bultynck G. Sneyers F, et al. Among authors: ghesquiere b. Cell Death Dis. 2023 Sep 8;14(9):600. doi: 10.1038/s41419-023-06120-4. Cell Death Dis. 2023. PMID: 37684238 Free PMC article.
13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation and exhaustion.
Kirchmair A, Nemati N, Lamberti G, Trefny M, Krogsdam A, Siller A, Hörtnagl P, Schumacher P, Sopper S, Sandbichler A, Zippelius A, Ghesquière B, Trajanoski Z. Kirchmair A, et al. Among authors: ghesquiere b. Front Immunol. 2023 Oct 19;14:1267816. doi: 10.3389/fimmu.2023.1267816. eCollection 2023. Front Immunol. 2023. PMID: 37928527 Free PMC article.
The effect of rewarming ischemia on tissue transcriptome and metabolome signatures: A clinical observational study in lung transplantation.
Van Slambrouck J, Loopmans S, Prisciandaro E, Barbarossa A, Kortleven P, Feys S, Vandervelde CM, Jin X, Cenik I, Moermans K, Fieuws S, Provoost AL, Willems A, De Leyn P, Van Veer H, Depypere L, Jansen Y, Pirenne J, Neyrinck A, Weynand B, Vanaudenaerde B, Carmeliet G, Vos R, Van Raemdonck D, Ghesquière B, Van Weyenbergh J, Ceulemans LJ. Van Slambrouck J, et al. Among authors: ghesquiere b. J Heart Lung Transplant. 2024 Oct 30:S1053-2498(24)01905-3. doi: 10.1016/j.healun.2024.10.020. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 39486771
142 results