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Page 1
Dopamine D1 receptor activation in the striatum is sufficient to drive reinforcement of anteceding cortical patterns.
Vendrell-Llopis N, Read J, Boggiano S, Hetzler B, Peitsinis Z, Stanley C, Visel M, Trauner D, Donthamsetti P, Carmena J, Lammel S, Isacoff EY. Vendrell-Llopis N, et al. Among authors: isacoff ey. Neuron. 2025 Jan 12:S0896-6273(24)00912-7. doi: 10.1016/j.neuron.2024.12.013. Online ahead of print. Neuron. 2025. PMID: 39814009 Free article.
Synapse-specific catecholaminergic modulation of neuronal glutamate release.
Bakshinska D, Liu WY, Schultz R, Stowers RS, Hoagland A, Cypranowska C, Stanley C, Younger SH, Newman ZL, Isacoff EY. Bakshinska D, et al. Among authors: isacoff ey. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2420496121. doi: 10.1073/pnas.2420496121. Epub 2024 Dec 30. Proc Natl Acad Sci U S A. 2025. PMID: 39793084 Free PMC article.
Subtype-specific conformational landscape of NMDA receptor gating.
Bleier J, Furtado de Mendonca PR, Habrian CH, Stanley C, Vyklicky V, Isacoff EY. Bleier J, et al. Among authors: isacoff ey. Cell Rep. 2024 Aug 27;43(8):114634. doi: 10.1016/j.celrep.2024.114634. Epub 2024 Aug 17. Cell Rep. 2024. PMID: 39154344 Free PMC article.
Coupling sensor to enzyme in the voltage sensing phosphatase.
Yu Y, Zhang L, Li B, Fu Z, Brohawn SG, Isacoff EY. Yu Y, et al. Among authors: isacoff ey. Nat Commun. 2024 Jul 30;15(1):6409. doi: 10.1038/s41467-024-50319-8. Nat Commun. 2024. PMID: 39080263 Free PMC article.
Development of covalent chemogenetic K2P channel activators.
Deal PE, Lee H, Mondal A, Lolicato M, Mendonça PRF, Black H, Jang S, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr. Deal PE, et al. Among authors: isacoff ey. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. doi: 10.1016/j.chembiol.2024.06.006. Cell Chem Biol. 2024. PMID: 39029456
Author Correction: Stepwise activation of a metabotropic glutamate receptor.
Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Krishna Kumar K, et al. Among authors: isacoff ey. Nature. 2024 May;629(8013):E13. doi: 10.1038/s41586-024-07470-5. Nature. 2024. PMID: 38702522 No abstract available.
Stepwise activation of a metabotropic glutamate receptor.
Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK. Krishna Kumar K, et al. Among authors: isacoff ey. Nature. 2024 May;629(8013):951-956. doi: 10.1038/s41586-024-07327-x. Epub 2024 Apr 17. Nature. 2024. PMID: 38632403
176 results