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Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H. Khoroshkin M, et al. Among authors: garcia k. Nat Commun. 2024 Sep 9;15(1):7872. doi: 10.1038/s41467-024-52215-7. Nat Commun. 2024. PMID: 39251607 Free PMC article.
RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon.
Yu J, Navickas A, Asgharian H, Culbertson B, Fish L, Garcia K, Olegario JP, Dermit M, Dodel M, Hänisch B, Luo Y, Weinberg EM, Dienstmann R, Warren RS, Mardakheh FK, Goodarzi H. Yu J, et al. Among authors: garcia k. Cancer Discov. 2020 Sep;10(9):1410-1423. doi: 10.1158/2159-8290.CD-19-1375. Epub 2020 Jun 8. Cancer Discov. 2020. PMID: 32513775 Free PMC article.
Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling.
Argouarch AR, Schultz N, Yang AC, Jang Y, Garcia K, Cosme CG, Corrales CI, Nana AL, Karydas AM, Spina S, Grinberg LT, Miller B, Wyss-Coray T, Abyzov A, Goodarzi H, Seeley WW, Kao AW. Argouarch AR, et al. Among authors: garcia k. Stem Cell Rev Rep. 2022 Dec;18(8):3050-3065. doi: 10.1007/s12015-022-10416-x. Epub 2022 Jul 9. Stem Cell Rev Rep. 2022. PMID: 35809166 Free PMC article.
Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma.
Samuel RM, Navickas A, Maynard A, Gaylord EA, Garcia K, Bhat S, Majd H, Richter MN, Elder N, Le D, Nguyen P, Shibata B, Llabata ML, Selleri L, Laird DJ, Darmanis S, Goodarzi H, Fattahi F. Samuel RM, et al. Among authors: garcia k. bioRxiv [Preprint]. 2023 Mar 7:2023.03.06.531220. doi: 10.1101/2023.03.06.531220. bioRxiv. 2023. PMID: 36945537 Free PMC article. Preprint.
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H. Navickas A, et al. Among authors: garcia k. Nat Cell Biol. 2023 Jun;25(6):892-903. doi: 10.1038/s41556-023-01141-9. Epub 2023 May 8. Nat Cell Biol. 2023. PMID: 37156909 Free PMC article.
Integrative identification of non-coding regulatory regions driving metastatic prostate cancer.
Woo BJ, Moussavi-Baygi R, Karner H, Karimzadeh M, Garcia K, Joshi T, Yin K, Navickas A, Gilbert LA, Wang B, Asgharian H, Feng FY, Goodarzi H. Woo BJ, et al. Among authors: garcia k. bioRxiv [Preprint]. 2023 Jun 2:2023.04.14.535921. doi: 10.1101/2023.04.14.535921. bioRxiv. 2023. Update in: Cell Rep. 2024 Sep 24;43(9):114764. doi: 10.1016/j.celrep.2024.114764 PMID: 37398273 Free PMC article. Updated. Preprint.
Functional microRNA-targeting drug discovery by graph-based deep learning.
Keshavarzi Arshadi A, Salem M, Karner H, Garcia K, Arab A, Yuan JS, Goodarzi H. Keshavarzi Arshadi A, et al. Among authors: garcia k. Patterns (N Y). 2024 Jan 3;5(1):100909. doi: 10.1016/j.patter.2023.100909. eCollection 2024 Jan 12. Patterns (N Y). 2024. PMID: 38264717 Free PMC article.
991 results