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Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells.
Balestrini PA, Abdelbaki A, McCarthy A, Devito L, Senner CE, Chen AE, Munusamy P, Blakeley P, Elder K, Snell P, Christie L, Serhal P, Odia RA, Sangrithi M, Niakan KK, Fogarty NME. Balestrini PA, et al. Among authors: niakan kk. Development. 2024 Sep 1;151(17):dev202778. doi: 10.1242/dev.202778. Epub 2024 Sep 10. Development. 2024. PMID: 39250534 Free PMC article.
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.
Blakeley P, Fogarty NM, del Valle I, Wamaitha SE, Hu TX, Elder K, Snell P, Christie L, Robson P, Niakan KK. Blakeley P, et al. Among authors: niakan kk. Development. 2015 Sep 15;142(18):3151-65. doi: 10.1242/dev.123547. Epub 2015 Aug 20. Development. 2015. PMID: 26293300 Free PMC article.
IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche.
Wamaitha SE, Grybel KJ, Alanis-Lobato G, Gerri C, Ogushi S, McCarthy A, Mahadevaiah SK, Healy L, Lea RA, Molina-Arcas M, Devito LG, Elder K, Snell P, Christie L, Downward J, Turner JMA, Niakan KK. Wamaitha SE, et al. Among authors: niakan kk. Nat Commun. 2020 Feb 7;11(1):764. doi: 10.1038/s41467-020-14629-x. Nat Commun. 2020. PMID: 32034154 Free PMC article.
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals.
Gerri C, McCarthy A, Mei Scott G, Regin M, Stamatiadis P, Brumm S, Simon CS, Lee J, Montesinos C, Hassitt C, Hockenhull S, Hampshire D, Elder K, Snell P, Christie L, Fouladi-Nashta AA, Van de Velde H, Niakan KK. Gerri C, et al. Among authors: niakan kk. Development. 2023 Apr 15;150(8):dev201112. doi: 10.1242/dev.201112. Epub 2023 Apr 20. Development. 2023. PMID: 36971487 Free PMC article.
Genome editing reveals a role for OCT4 in human embryogenesis.
Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, Bertero A, Turner JMA, Niakan KK. Fogarty NME, et al. Among authors: niakan kk. Nature. 2017 Oct 5;550(7674):67-73. doi: 10.1038/nature24033. Epub 2017 Sep 20. Nature. 2017. PMID: 28953884 Free PMC article.
Initiation of a conserved trophectoderm program in human, cow and mouse embryos.
Gerri C, McCarthy A, Alanis-Lobato G, Demtschenko A, Bruneau A, Loubersac S, Fogarty NME, Hampshire D, Elder K, Snell P, Christie L, David L, Van de Velde H, Fouladi-Nashta AA, Niakan KK. Gerri C, et al. Among authors: niakan kk. Nature. 2020 Nov;587(7834):443-447. doi: 10.1038/s41586-020-2759-x. Epub 2020 Sep 23. Nature. 2020. PMID: 32968278 Free PMC article.
57 results