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MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles.
Kammann T, Cai C, Sekine T, Mouchtaridi E, Boulouis C, Nilsén V, Ballesteros OR, Müller TR, Gao Y, Raineri EJM, Mily A, Adamo S, Constantz C, Niessl J, Weigel W, Kokkinou E, Stamper C, Marchalot A, Bassett J, Ferreira S, Rødahl I, Wild N, Brownlie D, Tibbitt C, Mak JYW, Fairlie DP, Leeansyah E, Michaelsson J, Marquardt N, Mjösberg J, Jorns C, Buggert M, Sandberg JK. Kammann T, et al. Among authors: gao y. Sci Immunol. 2024 Sep 6;9(99):eadn2362. doi: 10.1126/sciimmunol.adn2362. Epub 2024 Sep 6. Sci Immunol. 2024. PMID: 39241054
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.
Evren E, Ringqvist E, Tripathi KP, Sleiers N, Rives IC, Alisjahbana A, Gao Y, Sarhan D, Halle T, Sorini C, Lepzien R, Marquardt N, Michaëlsson J, Smed-Sörensen A, Botling J, Karlsson MCI, Villablanca EJ, Willinger T. Evren E, et al. Among authors: gao y. Immunity. 2021 Feb 9;54(2):259-275.e7. doi: 10.1016/j.immuni.2020.12.003. Epub 2020 Dec 30. Immunity. 2021. PMID: 33382972 Free article.
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.
Sandberg JT, Varnaitė R, Christ W, Chen P, Muvva JR, Maleki KT, García M, Dzidic M, Folkesson E, Skagerberg M, Ahlén G, Frelin L, Sällberg M, Eriksson LI, Rooyackers O, Sönnerborg A, Buggert M, Björkström NK, Aleman S, Strålin K, Klingström J, Ljunggren HG, Blom K, Gredmark-Russ S; Karolinska COVID‐19 Study Group. Sandberg JT, et al. Clin Transl Immunology. 2021 Jul 5;10(7):e1306. doi: 10.1002/cti2.1306. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34257967 Free PMC article.
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant.
Gao Y, Cai C, Grifoni A, Müller TR, Niessl J, Olofsson A, Humbert M, Hansson L, Österborg A, Bergman P, Chen P, Olsson A, Sandberg JK, Weiskopf D, Price DA, Ljunggren HG, Karlsson AC, Sette A, Aleman S, Buggert M. Gao Y, et al. Nat Med. 2022 Mar;28(3):472-476. doi: 10.1038/s41591-022-01700-x. Epub 2022 Jan 14. Nat Med. 2022. PMID: 35042228 Free PMC article.
NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals.
Cuapio A, Boulouis C, Filipovic I, Wullimann D, Kammann T, Parrot T, Chen P, Akber M, Gao Y, Hammer Q, Strunz B, Pérez Potti A, Rivera Ballesteros O, Lange J, Muvva JR, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Söderdahl G, Österborg A, Smith CIE, Bogdanovic G, Muschiol S, Hellgren F, Loré K, Sobkowiak MJ, Gabarrini G, Healy K, Sällberg Chen M, Alici E, Björkström NK, Buggert M, Ljungman P, Sandberg JK, Aleman S, Ljunggren HG. Cuapio A, et al. Among authors: gao y. Mol Med. 2022 Feb 8;28(1):20. doi: 10.1186/s10020-022-00443-2. Mol Med. 2022. PMID: 35135470 Free PMC article.
Elevated CD21low B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency.
Bergman P, Wullimann D, Gao Y, Wahren Borgström E, Norlin AC, Lind Enoksson S, Aleman S, Ljunggren HG, Buggert M, Smith CIE. Bergman P, et al. Among authors: gao y. J Clin Immunol. 2022 May;42(4):716-727. doi: 10.1007/s10875-022-01244-2. Epub 2022 Mar 15. J Clin Immunol. 2022. PMID: 35290571 Free PMC article. Clinical Trial.
MAIT cell compartment characteristics are associated with the immune response magnitude to the BNT162b2 mRNA anti-SARS-CoV-2 vaccine.
Boulouis C, Kammann T, Cuapio A, Parrot T, Gao Y, Mouchtaridi E, Wullimann D, Lange J, Chen P, Akber M, Rivera Ballesteros O, Muvva JR; COVAXID study group; Smith CIE, Vesterbacka J, Kieri O, Nowak P, Bergman P, Buggert M, Ljunggren HG, Aleman S, Sandberg JK. Boulouis C, et al. Among authors: gao y. Mol Med. 2022 May 13;28(1):54. doi: 10.1186/s10020-022-00484-7. Mol Med. 2022. PMID: 35562666 Free PMC article.
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Gao Y, Cai C, Wullimann D, Niessl J, Rivera-Ballesteros O, Chen P, Lange J, Cuapio A, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Perez-Potti A, Sekine T, Müller TR, Boulouis C, Kammann T, Parrot T, Muvva JR, Sobkowiak M, Healy K, Bogdanovic G, Muschiol S, Söderdahl G, Österborg A, Hellgren F, Grifoni A, Weiskopf D, Sette A, Loré K, Sällberg Chen M, Ljungman P, Sandberg JK, Smith CIE, Bergman P, Ljunggren HG, Aleman S, Buggert M. Gao Y, et al. Immunity. 2022 Sep 13;55(9):1732-1746.e5. doi: 10.1016/j.immuni.2022.07.005. Epub 2022 Jul 19. Immunity. 2022. PMID: 35961317 Free PMC article.
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age.
Humbert M, Olofsson A, Wullimann D, Niessl J, Hodcroft EB, Cai C, Gao Y, Sohlberg E, Dyrdak R, Mikaeloff F, Neogi U, Albert J, Malmberg KJ, Lund-Johansen F, Aleman S, Björkhem-Bergman L, Jenmalm MC, Ljunggren HG, Buggert M, Karlsson AC. Humbert M, et al. Among authors: gao y. Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2220320120. doi: 10.1073/pnas.2220320120. Epub 2023 Mar 14. Proc Natl Acad Sci U S A. 2023. PMID: 36917669 Free PMC article.
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