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Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside prodrugs against SARS-CoV-2 in mice.
Carlin AF, Beadle JR, Ardanuy J, Clark AE, Rhodes V, Garretson AF, Murphy JA, Valiaeva N, Schooley RT, Frieman MB, Hostetler KY. Carlin AF, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0103924. doi: 10.1128/aac.01039-24. Epub 2024 Sep 6. Antimicrob Agents Chemother. 2024. PMID: 39240093 Free PMC article.
Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs.
Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. Among authors: hostetler ky. bioRxiv [Preprint]. 2021 Jun 7:2020.08.26.269159. doi: 10.1101/2020.08.26.269159. bioRxiv. 2021. Update in: Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0115521. doi: 10.1128/AAC.01155-21 PMID: 32869033 Free PMC article. Updated. Preprint.
Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs.
Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0115521. doi: 10.1128/AAC.01155-21. Epub 2021 Jul 26. Antimicrob Agents Chemother. 2021. PMID: 34310217 Free PMC article.
The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons.
Wyles DL, Kaihara KA, Korba BE, Schooley RT, Beadle JR, Hostetler KY. Wyles DL, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2009 Jun;53(6):2660-2. doi: 10.1128/AAC.01546-08. Epub 2009 Mar 16. Antimicrob Agents Chemother. 2009. PMID: 19289518 Free PMC article.
180 results