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Predictors of incident stroke among individuals without coronary artery calcification: A pooled cohort analysis from the Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study, and Framingham Heart Study.
Hussain A, Johansen MC, Blaha MJ, Al-Mallah MH, Cainzos-Achirica M, Nambi V, Rotter JI, Guo X, Yao J, Rich SS, Patel J, McEvoy JW, Nasir K, Gottesman R, Blumenthal RS, Ballantyne CM, Virani SS, Al Rifai M. Hussain A, et al. Among authors: rotter ji. Vasc Med. 2024 Dec;29(6):632-639. doi: 10.1177/1358863X241270911. Epub 2024 Sep 6. Vasc Med. 2024. PMID: 39239865
Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.
Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT Jr, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, Hsu L, Jackson RD, Jarvik GP, Kim DS, Lakshminarayan K, Lange LA, Manichaikul A, Quinlan AR, Singleton AB, Thornton TA, Nickerson DA, Peters U, Rich SS; National Heart, Lung, and Blood Institute Exome Sequencing Project. Auer PL, et al. JAMA Neurol. 2015 Jul;72(7):781-8. doi: 10.1001/jamaneurol.2015.0582. JAMA Neurol. 2015. PMID: 25961151 Free PMC article.
Infertility and treatments used have minimal effects on first-trimester placental DNA methylation and gene expression.
Gonzalez TL, Schaub AM, Lee B, Cui J, Taylor KD, Dorfman AE, Goodarzi MO, Wang ET, Chen YI, Rotter JI, Hussaini R, Harakuni PM, Khan MH, Rich SS, Farber CR, Williams J 3rd, Pisarska MD. Gonzalez TL, et al. Among authors: rotter ji. Fertil Steril. 2023 Feb;119(2):301-312. doi: 10.1016/j.fertnstert.2022.11.010. Epub 2022 Nov 12. Fertil Steril. 2023. PMID: 36379261 Free article.
Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis.
Vargas LB, Lange LA, Ferrier K, Aguet F, Ardlie K, Gabriel S, Gupta N, Smith JD, Blackwell TW, Ding J, Durda P, Tracy RP, Liu Y, Taylor KD, Craig Johnson W, Rich SS, Rotter JI, Lange EM, Konigsberg IR. Vargas LB, et al. Among authors: rotter ji. Int J Obes (Lond). 2023 Feb;47(2):109-116. doi: 10.1038/s41366-022-01240-x. Epub 2022 Dec 3. Int J Obes (Lond). 2023. PMID: 36463326 Free PMC article.
Correlations between complex human phenotypes vary by genetic background, gender, and environment.
Elgart M, Goodman MO, Isasi C, Chen H, Morrison AC, de Vries PS, Xu H, Manichaikul AW, Guo X, Franceschini N, Psaty BM, Rich SS, Rotter JI, Lloyd-Jones DM, Fornage M, Correa A, Heard-Costa NL, Vasan RS, Hernandez R, Kaplan RC, Redline S; Trans-Omics for Precision Medicine (TOPMed) Consortium; Sofer T. Elgart M, et al. Among authors: rotter ji. Cell Rep Med. 2022 Dec 20;3(12):100844. doi: 10.1016/j.xcrm.2022.100844. Epub 2022 Dec 12. Cell Rep Med. 2022. PMID: 36513073 Free PMC article.
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.
Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Freedman BI, Göring HHH, Guo X, Haessler J, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Manichaikul A, Martin LW, McGarvey ST, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Sitlani CM, Smith JA, Taylor KD, Vasan RS, Willer CJ, Wilson JG, Yanek LR, Zhao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group; Rotter JI, Natarajan P, Peloso GM, Li Z, Lin X. Li X, et al. Among authors: rotter ji. Nat Genet. 2023 Jan;55(1):154-164. doi: 10.1038/s41588-022-01225-6. Epub 2022 Dec 23. Nat Genet. 2023. PMID: 36564505 Free PMC article.
Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants.
Young KL, Fisher V, Deng X, Brody JA, Graff M, Lim E, Lin BM, Xu H, Amin N, An P, Aslibekyan S, Fohner AE, Hidalgo B, Lenzini P, Kraaij R, Medina-Gomez C, Prokić I, Rivadeneira F, Sitlani C, Tao R, van Rooij J, Zhang D, Broome JG, Buth EJ, Heavner BD, Jain D, Smith AV, Barnes K, Boorgula MP, Chavan S, Darbar D, De Andrade M, Guo X, Haessler J, Irvin MR, Kalyani RR, Kardia SLR, Kooperberg C, Kim W, Mathias RA, McDonald ML, Mitchell BD, Peyser PA, Regan EA, Redline S, Reiner AP, Rich SS, Rotter JI, Smith JA, Weiss S, Wiggins KL, Yanek LR, Arnett D, Heard-Costa NL, Leal S, Lin D, McKnight B, Province M, van Duijn CM, North KE, Cupples LA, Liu CT. Young KL, et al. Among authors: rotter ji. HGG Adv. 2022 Nov 25;4(1):100163. doi: 10.1016/j.xhgg.2022.100163. eCollection 2023 Jan 12. HGG Adv. 2022. PMID: 36568030 Free PMC article.
MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study.
Kim JS, Manichaikul AW, Hoffman EA, Balte P, Anderson MR, Bernstein EJ, Madahar P, Oelsner EC, Kawut SM, Wysoczanski A, Laine AF, Adegunsoye A, Ma JZ, Taub MA, Mathias RA, Rich SS, Rotter JI, Noth I, Garcia CK, Barr RG, Podolanczuk AJ. Kim JS, et al. Among authors: rotter ji. Thorax. 2023 Jun;78(6):566-573. doi: 10.1136/thorax-2021-218139. Epub 2022 Aug 5. Thorax. 2023. PMID: 36690926 Free PMC article.
DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood.
Hahn J, Bressler J, Domingo-Relloso A, Chen MH, McCartney DL, Teumer A, van Dongen J, Kleber ME, Aïssi D, Swenson BR, Yao J, Zhao W, Huang J, Xia Y, Brown MR, Costeira R, de Geus EJC, Delgado GE, Dobson DA, Elliott P, Grabe HJ, Guo X, Harris SE, Huffman JE, Kardia SLR, Liu Y, Lorkowski S, Marioni RE, Nauck M, Ratliff SM, Sabater-Lleal M, Spector TD, Suchon P, Taylor KD, Thibord F, Trégouët DA, Wiggins KL, Willemsen G, Bell JT, Boomsma DI, Cole SA, Cox SR, Dehghan A, Greinacher A, Haack K, März W, Morange PE, Rotter JI, Sotoodehnia N, Tellez-Plaza M, Navas-Acien A, Smith JA, Johnson AD, Fornage M, Smith NL, Wolberg AS, Morrison AC, de Vries PS. Hahn J, et al. Among authors: rotter ji. J Thromb Haemost. 2023 May;21(5):1135-1147. doi: 10.1016/j.jtha.2023.01.015. Epub 2023 Jan 28. J Thromb Haemost. 2023. PMID: 36716967 Free PMC article.
1,255 results