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Page 1
SETD1B mutations confer apoptosis resistance and BCL2 independence in B cell lymphoma.
Portelinha A, Wang S, Parsa S, Jiang M, Gorelick AN, Mohanty S, Sharma S, de Stanchina E, Berishaj M, Zhao C, Heward J, Aryal NK, Tavana O, Wen J, Fitzgibbon J, Dogan A, Younes A, Melnick AM, Wendel HG. Portelinha A, et al. Among authors: heward j. J Exp Med. 2024 Oct 7;221(10):e20231143. doi: 10.1084/jem.20231143. Epub 2024 Sep 5. J Exp Med. 2024. PMID: 39235528
Precision medicine and lymphoma.
Heward JA, Kumar EA, Korfi K, Okosun J, Fitzgibbon J. Heward JA, et al. Curr Opin Hematol. 2018 Jul;25(4):329-334. doi: 10.1097/MOH.0000000000000437. Curr Opin Hematol. 2018. PMID: 29738334 Review.
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas.
Heward J, Konali L, D'Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T, Al Seraihi AF, Wang J, Korfi K, Araf S, Iqbal S, Bewicke-Copley F, Kumar E, Barisic D, Calaminici M, Clear A, Gribben J, Johnson P, Neve R, Cutillas P, Okosun J, Oppermann U, Melnick A, Packham G, Fitzgibbon J. Heward J, et al. Blood. 2021 Aug 5;138(5):370-381. doi: 10.1182/blood.2020008743. Blood. 2021. PMID: 33786580 Free PMC article.
Epigenetic dysregulation in follicular lymphoma.
Araf S, Okosun J, Koniali L, Fitzgibbon J, Heward J. Araf S, et al. Among authors: heward j. Epigenomics. 2016 Jan;8(1):77-84. doi: 10.2217/epi.15.96. Epub 2015 Dec 23. Epigenomics. 2016. PMID: 26698557 Free PMC article. Review.
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, Davies JK, Johnson P, Calaminici M, Montoto S, Auer R, Chelala C, Gribben JG, Graham TA, Fest T, Fitzgibbon J, Okosun J. Araf S, et al. Among authors: heward j. Leukemia. 2018 May;32(5):1261-1265. doi: 10.1038/s41375-018-0043-y. Epub 2018 Feb 8. Leukemia. 2018. PMID: 29568095 Free PMC article. No abstract available.
GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML.
Al Seraihi AF, Rio-Machin A, Tawana K, Bödör C, Wang J, Nagano A, Heward JA, Iqbal S, Best S, Lea N, McLornan D, Kozyra EJ, Wlodarski MW, Niemeyer CM, Scott H, Hahn C, Ellison A, Tummala H, Cardoso SR, Vulliamy T, Dokal I, Butler T, Smith M, Cavenagh J, Fitzgibbon J. Al Seraihi AF, et al. Among authors: heward ja. Leukemia. 2018 Nov;32(11):2502-2507. doi: 10.1038/s41375-018-0134-9. Epub 2018 Apr 19. Leukemia. 2018. PMID: 29749400 Free PMC article. No abstract available.
Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, Davies JK, Johnson P, Calaminici M, Montoto S, Auer R, Chelala C, Gribben JG, Graham TA, Fest T, Fitzgibbon J, Okosun J. Araf S, et al. Among authors: heward j. Leukemia. 2019 Jun;33(6):1540. doi: 10.1038/s41375-019-0425-9. Leukemia. 2019. PMID: 30903015 Free PMC article.
CREBBP histone acetyltransferase domain mutations predict response to mTOR inhibition in relapsed/refractory follicular lymphoma.
Kumar EA, Korfi K, Bewicke-Copley F, Close K, Heward J, Witzig T, Leukam M, Ansell S, Scott J, Clear A, Efeyan A, Green M, Siebert R, Peck B, Calaminici M, Wang J, Smith S, Novak A, Fitzgibbon J, Okosun J. Kumar EA, et al. Among authors: heward j. Br J Haematol. 2024 Nov;205(5):1804-1809. doi: 10.1111/bjh.19671. Epub 2024 Aug 26. Br J Haematol. 2024. PMID: 39188028
110 results