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Synthesis, biological evaluation and metadynamics simulations of novel N-methyl β-sheet breaker peptides as inhibitors of Alzheimer's β-amyloid fibrillogenesis.
Moraca F, Vespoli I, Mastroianni D, Piscopo V, Gaglione R, Arciello A, De Nisco M, Pacifico S, Catalanotti B, Pedatella S. Moraca F, et al. Among authors: de nisco m. RSC Med Chem. 2024 Apr 11;15(7):2286-2299. doi: 10.1039/d4md00057a. eCollection 2024 Jul 17. RSC Med Chem. 2024. PMID: 39026638
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening.
Lauro G, Manfra M, Pedatella S, Fischer K, Cantone V, Terracciano S, Bertamino A, Ostacolo C, Gomez-Monterrey I, De Nisco M, Riccio R, Novellino E, Werz O, Campiglia P, Bifulco G. Lauro G, et al. Among authors: de nisco m. Eur J Med Chem. 2017 Jan 5;125:278-287. doi: 10.1016/j.ejmech.2016.09.042. Epub 2016 Sep 14. Eur J Med Chem. 2017. PMID: 27688183
A general route to D- and L-six-membered nucleoside analogues.
Guaragna A, D'Alonzo D, De Nisco M, Pedatella S, Palumbo G. Guaragna A, et al. Among authors: de nisco m. Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):959-62. doi: 10.1080/15257770701508166. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18058517
20 results