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Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes.
bioRxiv [Preprint]. 2024 Aug 20:2024.08.19.607671. doi: 10.1101/2024.08.19.607671.
bioRxiv. 2024.
PMID: 39229041
Free PMC article.
Preprint.
A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis.
Ashkin EL, Tang YJ, Xu H, Hung KL, Belk J, Cai H, Lopez S, Dolcen DN, Hebert JD, Li R, Ruiz PA, Keal T, Andrejka L, Chang HY, Petrov DA, Dixon JR, Xu Z, Winslow MM.
Ashkin EL, et al.
bioRxiv [Preprint]. 2024 Sep 19:2024.09.14.613043. doi: 10.1101/2024.09.14.613043.
bioRxiv. 2024.
PMID: 39345539
Free PMC article.
Preprint.
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Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages.
Gonzalez MA, Lu DR, Yousefi M, Kroll A, Lo CH, Briseño CG, Watson JEV, Novitskiy S, Arias V, Zhou H, Plata Stapper A, Tsai MK, Ashkin EL, Murray CW, Li CM, Winslow MM, Tarbell KV.
Gonzalez MA, et al. Among authors: ashkin el.
J Exp Med. 2023 Jun 5;220(6):e20221472. doi: 10.1084/jem.20221472. Epub 2023 Mar 30.
J Exp Med. 2023.
PMID: 36995340
Free PMC article.
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Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
Yousefi M, Boross G, Weiss C, Murray CW, Hebert JD, Cai H, Ashkin EL, Karmakar S, Andrejka L, Chen L, Wang M, Tsai MK, Lin WY, Li C, Yakhchalian P, Colón CI, Chew SK, Chu P, Swanton C, Kunder CA, Petrov DA, Winslow MM.
Yousefi M, et al. Among authors: ashkin el.
Cancer Res. 2022 Apr 15;82(8):1589-1602. doi: 10.1158/0008-5472.CAN-22-0059.
Cancer Res. 2022.
PMID: 35425962
Free PMC article.
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A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer.
Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM.
Cai H, et al. Among authors: ashkin el.
Cancer Discov. 2021 Jul;11(7):1754-1773. doi: 10.1158/2159-8290.CD-20-1325. Epub 2021 Feb 19.
Cancer Discov. 2021.
PMID: 33608386
Free PMC article.
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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
Punt S, Malu S, McKenzie JA, Manrique SZ, Doorduijn EM, Mbofung RM, Williams L, Silverman DA, Ashkin EL, Dominguez AL, Wang Z, Chen JQ, Maiti SN, Tieu TN, Liu C, Xu C, Forget MA, Haymaker C, Khalili JS, Satani N, Muller F, Cooper LJN, Overwijk WW, Amaria RN, Bernatchez C, Heffernan TP, Peng W, Roszik J, Hwu P.
Punt S, et al. Among authors: ashkin el.
Cancer Immunol Immunother. 2021 Apr;70(4):1101-1113. doi: 10.1007/s00262-020-02748-9. Epub 2020 Oct 29.
Cancer Immunol Immunother. 2021.
PMID: 33123754
Free PMC article.
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