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Design of novel and highly selective SARS-CoV-2 main protease inhibitors.
Poli ANR, Tietjen I, Nandwana NK, Cassel J, Messick TE, Register ET, Keeney F, Rajaiah R, Verma AK, Pandey K, Acharya A, Byrareddy SN, Montaner LJ, Salvino JM. Poli ANR, et al. Among authors: salvino jm. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0056224. doi: 10.1128/aac.00562-24. Epub 2024 Sep 3. Antimicrob Agents Chemother. 2024. PMID: 39225484 Free PMC article.
The Natural Stilbenoid (-)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants.
Tietjen I, Cassel J, Register ET, Zhou XY, Messick TE, Keeney F, Lu LD, Beattie KD, Rali T, Tebas P, Ertl HCJ, Salvino JM, Davis RA, Montaner LJ. Tietjen I, et al. Among authors: salvino jm. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0077221. doi: 10.1128/AAC.00772-21. Epub 2021 Sep 20. Antimicrob Agents Chemother. 2021. PMID: 34543092 Free PMC article.
Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.
Matos-Hernández ML, Samples R, Dyer G, Casimir Montán VM, Morales-Colón CA, Salvino JM, Montaner LJ, Cassel JA, Messick TE, Tietjen I, Caro-Diaz EJE. Matos-Hernández ML, et al. Among authors: salvino jm. J Nat Prod. 2024 Jun 28;87(6):1513-1520. doi: 10.1021/acs.jnatprod.3c01071. Epub 2024 May 23. J Nat Prod. 2024. PMID: 38781491
Drug repositioning identifies salvinorin A and deacetylgedunin (DCG) enriched plant extracts as novel inhibitors of Mpro, RBD-ACE2 and TMPRRS2 proteins.
Shayo MJ, Samwel B, Shadrack DM, Cassel J, Salvino JM, Montaner LJ, Deogratias G, Tietjen I, Kiruri L, Hilonga S, Innocent E. Shayo MJ, et al. Among authors: salvino jm. RSC Adv. 2024 Jul 4;14(29):21203-21212. doi: 10.1039/d4ra02593h. eCollection 2024 Jun 27. RSC Adv. 2024. PMID: 38966817 Free PMC article.
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding.
Invernizzi L, Moyo P, Cassel J, Isaacs FJ, Salvino JM, Montaner LJ, Tietjen I, Maharaj V. Invernizzi L, et al. Among authors: salvino jm. Anal Bioanal Chem. 2022 May;414(13):3971-3985. doi: 10.1007/s00216-022-04041-3. Epub 2022 Apr 14. Anal Bioanal Chem. 2022. PMID: 35419694 Free PMC article.
5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2.
Majoumo-Mbe F, Sangbong NA, Tadjong Tcho A, Namba-Nzanguim CT, Simoben CV, Eni DB, Alhaji Isa M, Poli ANR, Cassel J, Salvino JM, Montaner LJ, Tietjen I, Ntie-Kang F. Majoumo-Mbe F, et al. Among authors: salvino jm. Chem Zvesti. 2024;78(6):3431-3441. doi: 10.1007/s11696-023-03274-5. Epub 2024 Mar 14. Chem Zvesti. 2024. PMID: 38685970 Free PMC article.
91 results