Cassel J - Search Results

1

Design of novel and highly selective SARS-CoV-2 main protease inhibitors.

Poli ANR, Tietjen I, Nandwana NK, Cassel J, Messick TE, Register ET, Keeney F, Rajaiah R, Verma AK, Pandey K, Acharya A, Byrareddy SN, Montaner LJ, Salvino JM. Poli ANR, et al. Among authors: cassel j. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0056224. doi: 10.1128/aac.00562-24. Epub 2024 Sep 3. Antimicrob Agents Chemother. 2024. PMID: 39225484 Free PMC article.

2

Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor.

Williams DE, Cassel J, Zhu JL, Yang JX, de Voogd NJ, Matainaho T, Salvino JM, Wang YA, Montaner LJ, Tietjen I, Andersen RJ. Williams DE, et al. Among authors: cassel j. J Nat Prod. 2023 Mar 24;86(3):582-588. doi: 10.1021/acs.jnatprod.2c01030. Epub 2023 Jan 19. J Nat Prod. 2023. PMID: 36657039 Free PMC article.

3

Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation.

Cui Y, Wang L, Ding Q, Shin J, Cassel J, Liu Q, Salvino JM, Tian B. Cui Y, et al. Among authors: cassel j. Nat Commun. 2023 Aug 1;14(1):4480. doi: 10.1038/s41467-023-39793-8. Nat Commun. 2023. PMID: 37528120 Free PMC article.

4

A high-throughput screening assay for silencing established HIV-1 macrophage infection identifies nucleoside analogs that perturb H3K9me3 on proviral genomes.

Yi Y, Zankharia U, Cassel JA, Lu F, Salvino JM, Lieberman PM, Collman RG. Yi Y, et al. J Virol. 2023 Aug 31;97(8):e0065323. doi: 10.1128/jvi.00653-23. Epub 2023 Aug 14. J Virol. 2023. PMID: 37578230 Free PMC article.

5

Synthesis and characterization of I-BET151 derivatives for use in identifying protein targets in the African trypanosome.

Poli ANR, Blyn RC, Buenconsejo GY, Hodanu M, Tang E, Danh C, Cassel J, Debler EW, Schulz D, Salvino JM. Poli ANR, et al. Among authors: cassel j. Curr Res Chem Biol. 2023;3:100047. doi: 10.1016/j.crchbi.2023.100047. Epub 2023 Nov 7. Curr Res Chem Biol. 2023. PMID: 38152610 Free PMC article.

6

A Tandem-Affinity Purification Method for Identification of Primary Intracellular Drug-Binding Proteins.

Islam S, Gour J, Beer T, Tang HY, Cassel J, Salvino JM, Busino L. Islam S, et al. Among authors: cassel j. ACS Chem Biol. 2024 Feb 16;19(2):233-242. doi: 10.1021/acschembio.3c00570. Epub 2024 Jan 25. ACS Chem Biol. 2024. PMID: 38271588

7

Synthesis, SARS-CoV-2 main protease inhibition, molecular docking and in silico ADME studies of furanochromene-quinoline hydrazone derivatives.

Shellenberger BM, Basile ON, Cassel J, Olsen MR, Salvino JM, Montaner LJ, Tietjen I, Henry GE. Shellenberger BM, et al. Among authors: cassel j. Bioorg Med Chem Lett. 2024 Apr 1;102:129679. doi: 10.1016/j.bmcl.2024.129679. Epub 2024 Feb 27. Bioorg Med Chem Lett. 2024. PMID: 38423371

8

Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.

Matos-Hernández ML, Samples R, Dyer G, Casimir Montán VM, Morales-Colón CA, Salvino JM, Montaner LJ, Cassel JA, Messick TE, Tietjen I, Caro-Diaz EJE. Matos-Hernández ML, et al. Among authors: cassel ja. J Nat Prod. 2024 Jun 28;87(6):1513-1520. doi: 10.1021/acs.jnatprod.3c01071. Epub 2024 May 23. J Nat Prod. 2024. PMID: 38781491

9

Cloning and Functional Characterization of Novel Human Neutralizing Anti-IFN-α and Anti-IFN-β Antibodies.

Papasavvas E, Lu L, Fair M, Oliva I, Cassel J, Majumdar S, Mounzer K, Kostman JR, Tebas P, Bar-Or A, Muthumani K, Montaner LJ. Papasavvas E, et al. Among authors: cassel j. J Immunol. 2024 Sep 15;213(6):808-822. doi: 10.4049/jimmunol.2400265. J Immunol. 2024. PMID: 39109927

10

A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry.

Nkwelle CE, Stephens U, Liang K, Cassel J, Salvino JM, Montaner LJ, Ndip RN, Esemu SN, Ntie-Kang F, Tietjen I. Nkwelle CE, et al. Among authors: cassel j. bioRxiv [Preprint]. 2024 Sep 11:2024.09.11.612557. doi: 10.1101/2024.09.11.612557. bioRxiv. 2024. PMID: 39314410 Free PMC article. Preprint.

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