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998 results

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Page 1
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma.
Kaushik AK, Tarangelo A, Boroughs LK, Ragavan M, Zhang Y, Wu CY, Li X, Ahumada K, Chiang JC, Tcheuyap VT, Saatchi F, Do QN, Yong C, Rosales T, Stevens C, Rao AD, Faubert B, Pachnis P, Zacharias LG, Vu H, Cai F, Mathews TP, Genovese G, Slusher BS, Kapur P, Sun X, Merritt M, Brugarolas J, DeBerardinis RJ. Kaushik AK, et al. Among authors: vu h. Sci Adv. 2022 Dec 16;8(50):eabp8293. doi: 10.1126/sciadv.abp8293. Epub 2022 Dec 16. Sci Adv. 2022. PMID: 36525494 Free PMC article.
Mitochondrial metabolism in primary and metastatic human kidney cancers.
Bezwada D, Lesner NP, Brooks B, Vu HS, Wu Z, Cai L, Kasitinon S, Kelekar S, Cai F, Aurora AB, Patrick M, Leach A, Ghandour R, Zhang Y, Do D, Sudderth J, Dumesnil D, House S, Rosales T, Poole AM, Lotan Y, Woldu S, Bagrodia A, Meng X, Cadeddu JA, Mishra P, Pedrosa I, Kapur P, Courtney KD, Malloy CR, Margulis V, DeBerardinis RJ. Bezwada D, et al. bioRxiv [Preprint]. 2023 Feb 7:2023.02.06.527285. doi: 10.1101/2023.02.06.527285. bioRxiv. 2023. Update in: Nature. 2024 Sep;633(8031):923-931. doi: 10.1038/s41586-024-07812-3 PMID: 36798172 Free PMC article. Updated. Preprint.
L-2-hydroxyglutaric aciduria - review of literature and case series.
Ahmed S, Siddiqui A, DeBerardinis RJ, Ni M, Gu Lai W, Cai F, Vu HS, Afroze B. Ahmed S, et al. Ann Med Surg (Lond). 2023 Apr 4;85(4):712-717. doi: 10.1097/MS9.0000000000000326. eCollection 2023 Apr. Ann Med Surg (Lond). 2023. PMID: 37113859 Free PMC article.
Electron transport chain inhibition increases cellular dependence on purine transport and salvage.
Wu Z, Bezwada D, Harris RC, Pan C, Nguyen PT, Faubert B, Cai L, Cai F, Vu HS, Chen H, Sandoval MM, Do D, Gu W, Zhang Y, Ko B, Brooks B, Kelekar S, Zhang Y, Zacharias LG, Oaxaca KC, Mathews TP, Garcia-Bermudez J, Ni M, DeBerardinis RJ. Wu Z, et al. Among authors: vu hs. bioRxiv [Preprint]. 2023 May 11:2023.05.11.540429. doi: 10.1101/2023.05.11.540429. bioRxiv. 2023. Update in: Cell Metab. 2024 Jul 2;36(7):1504-1520.e9. doi: 10.1016/j.cmet.2024.05.014 PMID: 37214913 Free PMC article. Updated. Preprint.
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases.
Parida PK, Marquez-Palencia M, Ghosh S, Khandelwal N, Kim K, Nair V, Liu XZ, Vu HS, Zacharias LG, Gonzalez-Ericsson PI, Sanders ME, Mobley BC, McDonald JG, Lemoff A, Peng Y, Lewis C, Vale G, Halberg N, Arteaga CL, Hanker AB, DeBerardinis RJ, Malladi S. Parida PK, et al. Nat Cancer. 2023 Jun;4(6):893-907. doi: 10.1038/s43018-023-00563-6. Epub 2023 May 29. Nat Cancer. 2023. PMID: 37248394 Free PMC article.
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples.
Cai F, Bezwada D, Cai L, Mahar R, Wu Z, Chang MC, Pachnis P, Yang C, Kelekar S, Gu W, Brooks B, Ko B, Vu HS, Mathews TP, Zacharias LG, Martin-Sandoval M, Do D, Oaxaca KC, Jin ES, Margulis V, Malloy CR, Merritt ME, DeBerardinis RJ. Cai F, et al. Cell Metab. 2023 Oct 3;35(10):1830-1843.e5. doi: 10.1016/j.cmet.2023.07.013. Epub 2023 Aug 22. Cell Metab. 2023. PMID: 37611583 Free PMC article.
Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis.
Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang CY, Tasdemir M, Fahrmann J, Grapov D, La Frano MR, Vu HS, Faubert B, Newman JW, McDonnell LA, Nezi L, Fiehn O, DeBerardinis RJ, Lengyel E. Mukherjee A, et al. Nat Metab. 2023 Sep;5(9):1563-1577. doi: 10.1038/s42255-023-00879-8. Epub 2023 Aug 31. Nat Metab. 2023. PMID: 37653041
998 results