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Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Aebi J, Atz K, Ametamey SM, Benz J, Blaising J, Butini S, Campiani G, Carreira EM, Collin L, De Lago E, Gazzi T, Gertsch J, Gobbi L, Guba W, Fernández-Ruiz J, Fingerle J, Haider A, He Y, Heitman LH, Honer M, Hunziker D, Kuhn B, Maccarrone M, Märki HP, Martin RE, Mohr P, Mu L, Nazaré M, Nippa DF, Oddi S, O'Hara F, Pacher P, Romero J, Röver S, Rufer AC, Schibli R, Schneider G, Stepan AF, Sykes DA, Ullmer C, Van der Stelt M, Veprintsev DB, Wittwer MB, Grether U. Aebi J, et al. Among authors: van der stelt m. Chimia (Aarau). 2024 Aug 21;78(7-8):499-512. doi: 10.2533/chimia.2024.499. Chimia (Aarau). 2024. PMID: 39221845 Free article.
A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance.
van der Krift F, Zijlmans DW, Shukla R, Javed A, Koukos PI, Schwarz LL, Timmermans-Sprang EP, Maas PE, Gahtory D, van den Nieuwboer M, Mol JA, Strous GJ, Bonvin AM, van der Stelt M, Veldhuizen EJ, Weingarth M, Vermeulen M, Klumperman J, Maurice MM. van der Krift F, et al. Among authors: van der stelt m, van den nieuwboer m. Life Sci Alliance. 2023 Aug 17;6(11):e202302058. doi: 10.26508/lsa.202302058. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37591722 Free PMC article.
The Concise Guide to PHARMACOLOGY 2023/24: Enzymes.
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Annett S, Boison D, Burns KE, Dessauer C, Gertsch J, Helsby NA, Izzo AA, Ostrom R, Papapetropoulos A, Pyne NJ, Pyne S, Robson T, Seifert R, Stasch JP, Szabo C, van der Stelt M, van der Vliet A, Watts V, Wong SS. Alexander SPH, et al. Among authors: van der stelt m, van der vliet a. Br J Pharmacol. 2023 Oct;180 Suppl 2:S289-S373. doi: 10.1111/bph.16181. Br J Pharmacol. 2023. PMID: 38123154 Free article. Review.
2-AG-Mediated Control of GABAergic Signaling Is Impaired in a Model of Epilepsy.
Colangeli R, Morena M, Werner A, Thompson RJ, van der Stelt M, Pittman QJ, Hill MN, Teskey GC. Colangeli R, et al. Among authors: van der stelt m. J Neurosci. 2023 Jan 25;43(4):571-583. doi: 10.1523/JNEUROSCI.0541-22.2022. Epub 2022 Dec 2. J Neurosci. 2023. PMID: 36460464 Free PMC article.
Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Berger N, van der Wel T, Hirschmugl B, Baernthaler T, Gindlhuber J, Fawzy N, Eichmann T, Birner-Gruenberger R, Zimmermann R, van der Stelt M, Wadsack C. Berger N, et al. Among authors: van der stelt m, van der wel t. Front Endocrinol (Lausanne). 2023 Feb 14;14:1092024. doi: 10.3389/fendo.2023.1092024. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36864832 Free PMC article.
163 results