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Page 1
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Aebi J, Atz K, Ametamey SM, Benz J, Blaising J, Butini S, Campiani G, Carreira EM, Collin L, De Lago E, Gazzi T, Gertsch J, Gobbi L, Guba W, Fernández-Ruiz J, Fingerle J, Haider A, He Y, Heitman LH, Honer M, Hunziker D, Kuhn B, Maccarrone M, Märki HP, Martin RE, Mohr P, Mu L, Nazaré M, Nippa DF, Oddi S, O'Hara F, Pacher P, Romero J, Röver S, Rufer AC, Schibli R, Schneider G, Stepan AF, Sykes DA, Ullmer C, Van der Stelt M, Veprintsev DB, Wittwer MB, Grether U. Aebi J, et al. Among authors: ametamey sm. Chimia (Aarau). 2024 Aug 21;78(7-8):499-512. doi: 10.2533/chimia.2024.499. Chimia (Aarau). 2024. PMID: 39221845 Free article.
Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates.
Haider A, Wang L, Gobbi L, Li Y, Chaudhary A, Zhou X, Chen J, Zhao C, Rong J, Xiao Z, Hou L, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Ahmed H, Crowe R, Honer M, Rominger A, Grether U, Liang SH, Ametamey SM. Haider A, et al. Among authors: ametamey sm. ACS Chem Neurosci. 2023 Oct 18;14(20):3752-3760. doi: 10.1021/acschemneuro.3c00222. Epub 2023 Oct 3. ACS Chem Neurosci. 2023. PMID: 37788055
Characterization of (R)- and (S)-[18F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Receptors.
Ahmed H, Wallimann R, Gisler L, Elghazawy NH, Gruber S, Keller C, Liang SH, Sippl W, Haider A, Ametamey SM. Ahmed H, et al. Among authors: ametamey sm. ACS Chem Neurosci. 2023 Dec 20;14(24):4323-4334. doi: 10.1021/acschemneuro.3c00519. Epub 2023 Dec 7. ACS Chem Neurosci. 2023. PMID: 38060344
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA Receptors.
Korff M, Chaudhary A, Li Y, Zhou X, Zhao C, Rong J, Chen J, Xiao Z, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Wang L, Abate C, Ahmed H, Crowe R, Schmidt TJ, Liang SH, Ametamey SM, Wünsch B, Haider A. Korff M, et al. Among authors: ametamey sm. J Med Chem. 2023 Dec 14;66(23):16018-16031. doi: 10.1021/acs.jmedchem.3c01441. Epub 2023 Nov 18. J Med Chem. 2023. PMID: 37979148
Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction.
Weidner P, Saar D, Söhn M, Schroeder T, Yu Y, Zöllner FG, Ponelies N, Zhou X, Zwicky A, Rohrbacher FN, Pattabiraman VR, Tanriver M, Bauer A, Ahmed H, Ametamey SM, Riffel P, Seger R, Bode JW, Wade RC, Ebert MPA, Kragelund BB, Burgermeister E. Weidner P, et al. Among authors: ametamey sm. Cancer Lett. 2024 Apr 28;588:216783. doi: 10.1016/j.canlet.2024.216783. Epub 2024 Mar 9. Cancer Lett. 2024. PMID: 38462034 Free article.
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives.
Ritter N, Disse P, Aymanns I, Mücher L, Schreiber JA, Brenker C, Strünker T, Schepmann D, Budde T, Strutz-Seebohm N, Ametamey SM, Wünsch B, Seebohm G. Ritter N, et al. Among authors: ametamey sm. Mol Neurobiol. 2023 Dec;60(12):7238-7252. doi: 10.1007/s12035-023-03526-1. Epub 2023 Aug 5. Mol Neurobiol. 2023. PMID: 37542648 Free PMC article.
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors.
Korff M, Chaudhary A, Li Y, Zhou X, Zhao C, Rong J, Chen J, Xiao Z, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Wang L, Abate C, Ahmed H, Crowe R, Liang SH, Ametamey SM, Wünsch B, Haider A. Korff M, et al. Among authors: ametamey sm. Res Sq [Preprint]. 2023 Jan 27:rs.3.rs-2516002. doi: 10.21203/rs.3.rs-2516002/v1. Res Sq. 2023. Update in: J Med Chem. 2023 Dec 14;66(23):16018-16031. doi: 10.1021/acs.jmedchem.3c01441 PMID: 36747738 Free PMC article. Updated. Preprint.
180 results