Saikosaponins from Bupleurum scorzonerifolium Willd. alleviates microglial pyroptosis in depression by binding and inhibiting P2X7 expression.
Bi Y, Li M, Wang Y, Yao J, Wang Y, Wang S, Zhuang L, Liu S, Li Z, Hao Z, Guan W, Pan J, Jiang P, Zhang Y, Kuang H, Chen Q, Zhang L, Yang B, Liu Y.
Bi Y, et al. Among authors: liu y, liu s.
Phytomedicine. 2025 Jan;136:156240. doi: 10.1016/j.phymed.2024.156240. Epub 2024 Nov 19.
Phytomedicine. 2025.
PMID: 39637473