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Design, synthesis, and structure-activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors.
Faouzi A, Arnaud A, Hallé F, Roussel J, Aymard M, Denavit V, Do CV, Mularoni A, Salah M, ElHady A, Pham TN, Bancet A, Le Borgne M, Terreux R, Barret R, Engel M, Lomberget T. Faouzi A, et al. RSC Med Chem. 2024 Oct 17. doi: 10.1039/d4md00537f. Online ahead of print. RSC Med Chem. 2024. PMID: 39430953 Free PMC article.
Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR.
Ople RS, Ramos-Gonzalez N, Li Q, Sobecks BL, Aydin D, Powers AS, Faouzi A, Polacco BJ, Bernhard SM, Appourchaux K, Sribhashyam S, Eans SO, Tsai BA, Dror RO, Varga BR, Wang H, Hüttenhain R, McLaughlin JP, Majumdar S. Ople RS, et al. Among authors: faouzi a. ACS Cent Sci. 2024 Jul 17;10(8):1490-1503. doi: 10.1021/acscentsci.4c00525. eCollection 2024 Aug 28. ACS Cent Sci. 2024. PMID: 39220695 Free PMC article.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, Slocum ST, Eans SO, Cameron MD, Al-Hasani R, Pan YX, Roth BL, McLaughlin JP, Skiniotis G, Katritch V, Kobilka BK, Majumdar S. Faouzi A, et al. Nature. 2023 Jan;613(7945):767-774. doi: 10.1038/s41586-022-05588-y. Epub 2022 Nov 30. Nature. 2023. PMID: 36450356 Free PMC article.
European Society of Cardiology: cardiovascular disease statistics 2021.
Timmis A, Vardas P, Townsend N, Torbica A, Katus H, De Smedt D, Gale CP, Maggioni AP, Petersen SE, Huculeci R, Kazakiewicz D, de Benito Rubio V, Ignatiuk B, Raisi-Estabragh Z, Pawlak A, Karagiannidis E, Treskes R, Gaita D, Beltrame JF, McConnachie A, Bardinet I, Graham I, Flather M, Elliott P, Mossialos EA, Weidinger F, Achenbach S; Atlas Writing Group, European Society of Cardiology. Timmis A, et al. Eur Heart J. 2022 Feb 22;43(8):716-799. doi: 10.1093/eurheartj/ehab892. Eur Heart J. 2022. PMID: 35016208 Free article.
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects.
Chakraborty S, DiBerto JF, Faouzi A, Bernhard SM, Gutridge AM, Ramsey S, Zhou Y, Provasi D, Nuthikattu N, Jilakara R, Nelson MNF, Asher WB, Eans SO, Wilson LL, Chintala SM, Filizola M, van Rijn RM, Margolis EB, Roth BL, McLaughlin JP, Che T, Sames D, Javitch JA, Majumdar S. Chakraborty S, et al. Among authors: faouzi a. J Med Chem. 2021 Sep 23;64(18):13873-13892. doi: 10.1021/acs.jmedchem.1c01273. Epub 2021 Sep 10. J Med Chem. 2021. PMID: 34505767 Free PMC article.
[Gout affecting the hip in a 57-year-old woman: case report].
Nabil D, Hassen C, Walid B, Issam K, Mouna S, Wassia K, Faouzi A. Nabil D, et al. Among authors: faouzi a. Pan Afr Med J. 2020 Dec 3;37:306. doi: 10.11604/pamj.2020.37.306.20859. eCollection 2020. Pan Afr Med J. 2020. PMID: 33654525 Free PMC article. French.
29 results