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Page 1
Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells.
Penaud-Budloo M, Lecomte E, Lecomte Q, Pacouret S, Broucque F, Guy-Duché A, Dupont JB, Jeanson-Leh L, Robin C, Blouin V, Ayuso E, Adjali O. Penaud-Budloo M, et al. Among authors: dupont jb. Mol Ther Methods Clin Dev. 2024 Jul 25;32(3):101305. doi: 10.1016/j.omtm.2024.101305. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39220637 Free PMC article.
Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA.
Dupont JB, Tournaire B, Georger C, Marolleau B, Jeanson-Leh L, Ledevin M, Lindenbaum P, Lecomte E, Cogné B, Dubreil L, Larcher T, Gjata B, Van Wittenberghe L, Le Guiner C, Penaud-Budloo M, Snyder RO, Moullier P, Léger A. Dupont JB, et al. Mol Ther Methods Clin Dev. 2015 Apr 8;2:15010. doi: 10.1038/mtm.2015.10. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26029721 Free PMC article.
Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing.
Lecomte E, Tournaire B, Cogné B, Dupont JB, Lindenbaum P, Martin-Fontaine M, Broucque F, Robin C, Hebben M, Merten OW, Blouin V, François A, Redon R, Moullier P, Léger A. Lecomte E, et al. Among authors: dupont jb. Mol Ther Nucleic Acids. 2015 Oct 27;4(10):e260. doi: 10.1038/mtna.2015.32. Mol Ther Nucleic Acids. 2015. PMID: 26506038 Free PMC article.
Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice.
Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW. Hamm SE, et al. Among authors: dupont jb. Mol Ther Methods Clin Dev. 2021 Mar 3;21:144-160. doi: 10.1016/j.omtm.2021.02.024. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33850950 Free PMC article.
Dystrophin deficiency impairs cell junction formation during embryonic myogenesis.
Mozin E, Massouridès E, Mournetas V, Lièvre C, Bourdon A, Jackson DL, Packer JS, Seong J, Trapnell C, Le Guiner C, Adjali O, Pinset C, Mack DL, Dupont JB. Mozin E, et al. Among authors: dupont jb. bioRxiv [Preprint]. 2024 Apr 8:2023.12.05.569919. doi: 10.1101/2023.12.05.569919. bioRxiv. 2024. Update in: iScience. 2024 Jun 11;27(7):110242. doi: 10.1016/j.isci.2024.110242 PMID: 38106055 Free PMC article. Updated. Preprint.
Genetic diseases in the omics era.
Dupont JB. Dupont JB. Mol Ther. 2021 Aug 4;29(8):2389-2390. doi: 10.1016/j.ymthe.2021.07.007. Epub 2021 Jul 23. Mol Ther. 2021. PMID: 34297919 Free PMC article. No abstract available.
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