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Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer.
McIntyre CA, Grimont A, Park J, Meng Y, Sisso WJ, Seier K, Jang GH, Walch H, Aveson VG, Falvo DJ, Fall WB, Chan CW, Wenger A, Ecker BL, Pulvirenti A, Gelfer R, Zafra MP, Schultz N, Park W, O'Reilly EM, Houlihan SL, Alonso A, Hissong E, Church GM, Mason CE, Siolas D, Notta F, Gonen M, Dow LE, Jarnagin WR, Chandwani R. McIntyre CA, et al. Among authors: dow le. Cancer Cell. 2024 Sep 9;42(9):1614-1629.e5. doi: 10.1016/j.ccell.2024.08.002. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214094
Somatic Genome Editing Goes Viral.
Zafra MP, Dow LE. Zafra MP, et al. Among authors: dow le. Trends Mol Med. 2016 Oct;22(10):831-833. doi: 10.1016/j.molmed.2016.08.004. Epub 2016 Aug 20. Trends Mol Med. 2016. PMID: 27555346 Free PMC article.
Base editing the mammalian genome.
Schatoff EM, Zafra MP, Dow LE. Schatoff EM, et al. Among authors: dow le. Methods. 2019 Jul 15;164-165:100-108. doi: 10.1016/j.ymeth.2019.02.022. Epub 2019 Mar 2. Methods. 2019. PMID: 30836137 Free PMC article. Review.
Adenine base editing in an adult mouse model of tyrosinaemia.
Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W. Song CQ, et al. Among authors: dow le. Nat Biomed Eng. 2020 Jan;4(1):125-130. doi: 10.1038/s41551-019-0357-8. Epub 2019 Feb 25. Nat Biomed Eng. 2020. PMID: 31740768 Free PMC article.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
Annunziato S, Lutz C, Henneman L, Bhin J, Wong K, Siteur B, van Gerwen B, de Korte-Grimmerink R, Zafra MP, Schatoff EM, Drenth AP, van der Burg E, Eijkman T, Mukherjee S, Boroviak K, Wessels LF, van de Ven M, Huijbers IJ, Adams DJ, Dow LE, Jonkers J. Annunziato S, et al. Among authors: dow le. EMBO J. 2020 Mar 2;39(5):e102169. doi: 10.15252/embj.2019102169. Epub 2020 Jan 13. EMBO J. 2020. PMID: 31930530 Free PMC article.
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Han T, Goswami S, Hu Y, Tang F, Zafra MP, Murphy C, Cao Z, Poirier JT, Khurana E, Elemento O, Hechtman JF, Ganesh K, Yaeger R, Dow LE. Han T, et al. Among authors: dow le. Cancer Discov. 2020 Oct;10(10):1590-1609. doi: 10.1158/2159-8290.CD-19-1536. Epub 2020 Jun 16. Cancer Discov. 2020. PMID: 32546576 Free PMC article.
90 results