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An exosome-based liquid biopsy predicts depth of response and survival outcomes to cetuximab and panitumumab in metastatic colorectal cancer: The EXONERATE Study.
Xu C, Mannucci A, Esposito F, Oliveres H, Alonso Orduña V, Yubero A, Fernández-Martos C, Salud A, Gallego J, Martin-Richard M, Fernández-Plana J, Guillot M, Aparicio J, Fakih M, Kopetz S, Feliu J, Maurel J, Goel A. Xu C, et al. Among authors: kopetz s. Clin Cancer Res. 2025 Jan 17. doi: 10.1158/1078-0432.CCR-24-1934. Online ahead of print. Clin Cancer Res. 2025. PMID: 39820673
Impact of co-mutations and transcriptional signatures in non-small cell lung cancer patients treated with adagrasib in the KRYSTAL-1 trial.
Negrao MV, Paula AG, Molkentine D, Hover L, Nilsson M, Vokes N, Engstrom L, Calinisan A, Briere DM, Waters L, Hallin J, Diao L, Altan M, Blumenschein GR, Skoulidis F, Wang J, Kopetz SE, Hong DS, Gibbons DL, Olson P, Christensen JG, Heymach JV. Negrao MV, et al. Among authors: kopetz se. Clin Cancer Res. 2025 Jan 13. doi: 10.1158/1078-0432.CCR-24-2310. Online ahead of print. Clin Cancer Res. 2025. PMID: 39804166
Gene signatures derived from transcriptomic-causal networks stratify colorectal cancer patients for effective targeted therapy.
Yazdani A, Lenz HJ, Pillonetto G, Mendez-Giraldez R, Yazdani A, Sanoff H, Hadi R, Samiei E, Venook AP, Ratain MJ, Rashid N, Vincent BG, Qu X, Wen Y, Kosorok M, Symmans WF, Shen JPYC, Lee MS, Kopetz S, Nixon AB, Bertagnolli MM, Perou CM, Innocenti F. Yazdani A, et al. Among authors: kopetz s. Commun Med (Lond). 2025 Jan 8;5(1):9. doi: 10.1038/s43856-024-00728-z. Commun Med (Lond). 2025. PMID: 39779996 Free PMC article.
Mutational and co-mutational landscape of early onset colorectal cancer.
Alshenaifi JY, Vetere G, Maddalena G, Yousef M, White MG, Shen JP, Vilar E, Parseghian C, Dasari A, Morris VK, Huey R, Overman MJ, Wolff R, Raghav KP, Willis J, Alfaro K, Futreal A, You YN, Kopetz S. Alshenaifi JY, et al. Among authors: kopetz s. Biomarkers. 2025 Jan 9:1-13. doi: 10.1080/1354750X.2024.2447089. Online ahead of print. Biomarkers. 2025. PMID: 39761813
Trastuzumab Plus Pertuzumab Versus Cetuximab Plus Irinotecan in Patients With RAS/BRAF Wild-Type, HER2-Positive, Metastatic Colorectal Cancer (S1613): A Randomized Phase II Trial.
Raghav KPS, Guthrie KA, Tan B Jr, Denlinger CS, Fakih M, Overman MJ, Dasari NA, Corum LR, Hicks LG, Patel MS, Esparaz BT, Kazmi SM, Alluri N, Colby S, Gholami S, Gold PJ, Chiorean EG, Kopetz S, Hochster HS, Philip PA. Raghav KPS, et al. Among authors: kopetz s. J Clin Oncol. 2025 Jan 6:JCO2401710. doi: 10.1200/JCO-24-01710. Online ahead of print. J Clin Oncol. 2025. PMID: 39761503
The Landscape of Circulating Tumor DNA (ctDNA) in Appendiceal Adenocarcinoma.
White MG, Zeineddine MA, Fallon EA, Zeineddine FA, Dansby J, Chowdhury S, Hornstein N, Yousef A, Yousef M, Bhutiani N, Gu Y, Kee B, Dasari A, Overman MJ, Raghav K, Kopetz S, Uppal A, Taggart M, Newhook T, Fournier K, Helmink B, Drusbosky LM, Shen JP. White MG, et al. Among authors: kopetz s. Clin Cancer Res. 2024 Dec 16. doi: 10.1158/1078-0432.CCR-24-2474. Online ahead of print. Clin Cancer Res. 2024. PMID: 39679931
A deconvolution framework that uses single-cell sequencing plus a small benchmark data set for accurate analysis of cell type ratios in complex tissue samples.
Guo S, Liu X, Cheng X, Jiang Y, Ji S, Liang Q, Koval A, Li Y, Owen LA, Kim IK, Aparicio A, Lee S, Sood AK, Kopetz S, Shen JP, Weinstein JN, DeAngelis MM, Chen R, Wang W. Guo S, et al. Among authors: kopetz s. Genome Res. 2025 Jan 22;35(1):147-161. doi: 10.1101/gr.278822.123. Genome Res. 2025. PMID: 39586714 Free article.
472 results