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B cell-based therapy produces antibodies that inhibit glioblastoma growth.
Wang S, Castro BA, Katz JL, Arrieta V, Najem H, Vazquez-Cervantes GI, Wan H, Olson IE, Hou D, Dapash M, Billingham LK, Chia TY, Wei C, Rashidi A, Platanias LC, McCortney K, Horbinski CM, Stupp R, Zhang P, Ahmed AU, Sonabend AM, Heimberger AB, Lesniak MS, Riviere-Cazaux C, Burns T, Miska J, Fischietti M, Lee-Chang C. Wang S, et al. Among authors: horbinski cm. J Clin Invest. 2024 Aug 29;134(20):e177384. doi: 10.1172/JCI177384. J Clin Invest. 2024. PMID: 39207859 Free PMC article.
NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. Choudhury A, et al. Among authors: horbinski cm. bioRxiv [Preprint]. 2023 Jul 11:2023.07.10.548456. doi: 10.1101/2023.07.10.548456. bioRxiv. 2023. Update in: Cancer Discov. 2024 Oct 4;14(10):1823-1837. doi: 10.1158/2159-8290.CD-23-1459 PMID: 37503127 Free PMC article. Updated. Preprint.
Long-term outcomes of central neurocytoma - an institutional experience.
Yang Y, Wadhwani N, Shimomura A, Zheng S, Chandler J, Lesniak MS, Tate MC, Sonabend AM, Kalapurakal J, Horbinski C, Lukas R, Stupp R, Kumthekar P, Sachdev S. Yang Y, et al. J Neurooncol. 2024 Aug;169(1):195-201. doi: 10.1007/s11060-024-04713-3. Epub 2024 Jun 12. J Neurooncol. 2024. PMID: 38865011
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.
Kim KS, Habashy K, Gould A, Zhao J, Najem H, Amidei C, Saganty R, Arrieta VA, Dmello C, Chen L, Zhang DY, Castro B, Billingham L, Levey D, Huber O, Marques M, Savitsky DA, Morin BM, Muzzio M, Canney M, Horbinski C, Zhang P, Miska J, Padney S, Zhang B, Rabadan R, Phillips JJ, Butowski N, Heimberger AB, Hu J, Stupp R, Chand D, Lee-Chang C, Sonabend AM. Kim KS, et al. Neuro Oncol. 2024 Nov 4;26(11):2044-2060. doi: 10.1093/neuonc/noae135. Neuro Oncol. 2024. PMID: 39028616
RNA splicing as a biomarker and phenotypic driver of meningioma DNA-methylation groups.
Leclair NK, Choudury A, Chen WC, Magill ST, McCortney K, Horbinski CM, Chen Z, Goldschmidt E, Eaton CD, Bulsara KR, Bi WL, Patel AJ, Sahm F, Raleigh D, Anczukow O. Leclair NK, et al. Among authors: horbinski cm. Neuro Oncol. 2024 Dec 5;26(12):2222-2236. doi: 10.1093/neuonc/noae150. Neuro Oncol. 2024. PMID: 39093629 Free PMC article.
Pediatric glioma immune profiling identifies TIM3 as a therapeutic target in BRAF fusion pilocytic astrocytoma.
Tripathi S, Najem H, Dussold C, Pacheco S, Du R, Sooreshjani M, Hurley L, Chandler JP, Stupp R, Sonabend AM, Horbinski CM, Lukas RV, Xiu J, Lopez G, Nicolaides TP, Brown V, Wadhwani NR, Lam SK, James CD, Rao G, Castro MG, Heimberger AB, DeCuypere M. Tripathi S, et al. Among authors: horbinski cm. J Clin Invest. 2024 Aug 13;134(19):e177413. doi: 10.1172/JCI177413. J Clin Invest. 2024. PMID: 39137048 Free PMC article.
Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review.
Horbinski C, Solomon DA, Lukas RV, Packer RJ, Brastianos P, Wen PY, Snuderl M, Berger MS, Chang S, Fouladi M, Phillips JJ, Nabors B, Brat DJ, Huse JT, Aldape K, Sarkaria JN, Holdhoff M, Burns TC, Peters KB, Mellinghoff IK, Arons D, Galanis E. Horbinski C, et al. JAMA Oncol. 2024 Dec 26. doi: 10.1001/jamaoncol.2024.5506. Online ahead of print. JAMA Oncol. 2024. PMID: 39724142
81 results