Hemsley K - Search Results

1

Application of diceCT to Study the Development of the Zika Virus-Infected Mouse Brain.

Green AL, Cowell EC, Carr LM, Hemsley K, Sherratt E, Collins-Praino LE, Carr JM. Green AL, et al. Among authors: hemsley k. Viruses. 2024 Aug 20;16(8):1330. doi: 10.3390/v16081330. Viruses. 2024. PMID: 39205304 Free PMC article.

2

Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes.

Fraldi A, Hemsley K, Crawley A, Lombardi A, Lau A, Sutherland L, Auricchio A, Ballabio A, Hopwood JJ. Fraldi A, et al. Among authors: hemsley k. Hum Mol Genet. 2007 Nov 15;16(22):2693-702. doi: 10.1093/hmg/ddm223. Epub 2007 Aug 27. Hum Mol Genet. 2007. PMID: 17725987

3

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment.

Bhattacharjee R, Jolly LA, Corbett MA, Wee IC, Rao SR, Gardner AE, Ritchie T, van Hugte EJH, Ciptasari U, Piltz S, Noll JE, Nazri N, van Eyk CL, White M, Fornarino D, Poulton C, Baynam G, Collins-Praino LE, Snel MF, Nadif Kasri N, Hemsley KM, Thomas PQ, Kumar R, Gecz J. Bhattacharjee R, et al. Among authors: hemsley km. Nat Commun. 2024 Feb 8;15(1):1210. doi: 10.1038/s41467-024-45121-5. Nat Commun. 2024. PMID: 38331934 Free PMC article.

4

The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.

Winner LK, Beard H, Karageorgos L, Smith NJ, Hopwood JJ, Hemsley KM. Winner LK, et al. Among authors: hemsley km. Biochim Biophys Acta Mol Basis Dis. 2023 Apr;1869(4):166658. doi: 10.1016/j.bbadis.2023.166658. Epub 2023 Jan 29. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36720445 Free article.

5

Repetitive, non-invasive imaging of neurodegeneration, and prevention of it with gene replacement, in mice with Sanfilippo syndrome.

Hemsley KM, Beard H, Chidlow G, Mammone T, Winner LK, Neumann D, King B, Snel MF, Trim PJ, Casson RJ. Hemsley KM, et al. Exp Neurol. 2024 Jan;371:114610. doi: 10.1016/j.expneurol.2023.114610. Epub 2023 Nov 8. Exp Neurol. 2024. PMID: 37944880

6

Early disease course is unaltered in mucopolysaccharidosis type IIIA (MPS IIIA) mice lacking α-synuclein.

Soe K, Beard H, Neumann D, Trim PJ, Duplock S, Snel MF, Hopwood JJ, Hemsley KM. Soe K, et al. Among authors: hemsley km. Neuropathol Appl Neurobiol. 2019 Dec;45(7):715-731. doi: 10.1111/nan.12548. Epub 2019 Apr 25. Neuropathol Appl Neurobiol. 2019. PMID: 30907009

7

Is the eye a window to the brain in Sanfilippo syndrome?

Beard H, Chidlow G, Neumann D, Nazri N, Douglass M, Trim PJ, Snel MF, Casson RJ, Hemsley KM. Beard H, et al. Acta Neuropathol Commun. 2020 Nov 17;8(1):194. doi: 10.1186/s40478-020-01070-w. Acta Neuropathol Commun. 2020. PMID: 33203474 Free PMC article.

8

Axonal dystrophy in the brain of mice with Sanfilippo syndrome.

Beard H, Hassiotis S, Gai WP, Parkinson-Lawrence E, Hopwood JJ, Hemsley KM. Beard H, et al. Exp Neurol. 2017 Sep;295:243-255. doi: 10.1016/j.expneurol.2017.06.010. Epub 2017 Jun 8. Exp Neurol. 2017. PMID: 28601604

9

Neuronal-specific impairment of heparan sulfate degradation in Drosophila reveals pathogenic mechanisms for Mucopolysaccharidosis type IIIA.

Webber DL, Choo A, Hewson LJ, Trim PJ, Snel MF, Hopwood JJ, Richards RI, Hemsley KM, O'Keefe LV. Webber DL, et al. Exp Neurol. 2018 May;303:38-47. doi: 10.1016/j.expneurol.2018.01.020. Epub 2018 Feb 2. Exp Neurol. 2018. PMID: 29408731

10

Survival and engraftment of mouse embryonic stem cell-derived implants in the guinea pig brain.

Robinson AJ, Meedeniya AC, Hemsley KM, Auclair D, Crawley AC, Hopwood JJ. Robinson AJ, et al. Among authors: hemsley km. Neurosci Res. 2005 Oct;53(2):161-8. doi: 10.1016/j.neures.2005.06.010. Neurosci Res. 2005. PMID: 16023750

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