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Page 1
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity.
Soll D, Chu CF, Sun S, Lutz V, Arunkumar M, Gachechiladze M, Schäuble S, Alissa-Alkhalaf M, Nguyen T, Khalil MA, Garcia-Ribelles I, Mueller M, Buder K, Michalke B, Panagiotou G, Ziegler-Martin K, Benz P, Schatzlmaier P, Hiller K, Stockinger H, Luu M, Schober K, Moosmann C, Schamel WW, Huber M, Zielinski CE. Soll D, et al. Among authors: schatzlmaier p. Nat Immunol. 2024 Oct;25(10):1830-1844. doi: 10.1038/s41590-024-01918-6. Epub 2024 Aug 28. Nat Immunol. 2024. PMID: 39198632 Free PMC article.
Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion.
Platzer R, Hellmeier J, Göhring J, Perez ID, Schatzlmaier P, Bodner C, Focke-Tejkl M, Schütz GJ, Sevcsik E, Stockinger H, Brameshuber M, Huppa JB. Platzer R, et al. Among authors: schatzlmaier p. EMBO Rep. 2023 Nov 6;24(11):e57842. doi: 10.15252/embr.202357842. Epub 2023 Sep 28. EMBO Rep. 2023. PMID: 37768718 Free PMC article.
The small molecule inhibitor BX-795 uncouples IL-2 production from inhibition of Th2 inflammation and induces CD4+ T cells resembling iTreg.
Tauber PA, Kratzer B, Schatzlmaier P, Smole U, Köhler C, Rausch L, Kranich J, Trapin D, Neunkirchner A, Zabel M, Jutz S, Steinberger P, Gadermaier G, Brocker T, Stockinger H, Derdak S, Pickl WF. Tauber PA, et al. Among authors: schatzlmaier p. Front Immunol. 2023 Apr 6;14:1094694. doi: 10.3389/fimmu.2023.1094694. eCollection 2023. Front Immunol. 2023. PMID: 37090735 Free PMC article.
24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation.
Zhu C, Boucheron N, Müller AC, Májek P, Claudel T, Halilbasic E, Baazim H, Lercher A, Viczenczova C, Hainberger D, Preglej T, Sandner L, Alteneder M, Gülich AF, Khan M, Hamminger P, Remetic J, Ohradanova-Repic A, Schatzlmaier P, Donner C, Fuchs CD, Stojakovic T, Scharnagl H, Sakaguchi S, Weichhart T, Bergthaler A, Stockinger H, Ellmeier W, Trauner M. Zhu C, et al. Among authors: schatzlmaier p. J Hepatol. 2021 Nov;75(5):1164-1176. doi: 10.1016/j.jhep.2021.06.036. Epub 2021 Jul 7. J Hepatol. 2021. PMID: 34242699 Free PMC article.
Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.
Forster F, Paster W, Supper V, Schatzlmaier P, Sunzenauer S, Ostler N, Saliba A, Eckerstorfer P, Britzen-Laurent N, Schütz G, Schmid JA, Zlabinger GJ, Naschberger E, Stürzl M, Stockinger H. Forster F, et al. Among authors: schatzlmaier p. J Immunol. 2014 Jan 15;192(2):771-81. doi: 10.4049/jimmunol.1300377. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337748